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First received: September 22, 2025

Clinical Trial: Ozone Therapy for Oral Mucositis in Patients Receiving Head and Neck Cancer Radio- and Chemotherapy

Study Status: COMPLETED

Recruit Status: COMPLETED

Condition: Oral Mucositis

Study Type: INTERVENTIONAL


Official Title: Ozone Therapy for the Treatment of Oral Mucositis and/or Stomatitis in Patients Undergoing Radio- and Chemotherapy in the Head and Neck District: A Prospective Clinical Trial

Brief Summary: Oral mucositis is a frequent and painful side effect of radio- and chemotherapy, especially in patients with head and neck cancer.It can cause severe discomfort, difficulty eating and swallowing, infections, and interruptions of cancer treatment.This study evaluates the effectiveness of ozone therapy, delivered both professionally in the dental clinic and at home with ozone-based toothpaste, mouthrinse, and gel, in reducing symptoms of oral mucositis and stomatitis.Fifty-eight adult cancer patients with oral…

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