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First received: May 19, 2025

Clinical Trial: A Strep Throat Controlled Human Infection Trial in Healthy Adults

Study Status: COMPLETED

Recruit Status: COMPLETED

Condition: Streptococcus Pyogenes Pharyngitis

Study Type: INTERVENTIONAL


Official Title: CHIVAS- M1 (Controlled Human Infection for Vaccination Against Streptococcus Pyogenes M1UK): Expanding the Scope of Experimental Human Streptococcus Pyogenes Pharyngitis

Brief Summary: This aim of this study is to further develop a new way to study the bacteria that causes pharyngitis (strep throat).The scientific name for this bacterium is Streptococcus pyogenes and it is commonly known as Strep A. Strep A is a common type of bacteria that can cause various infections.These range from skin infections and strep throat to more serious conditions like rheumatic heart disease.In recent years there has been an increase in severe Strep A infections in most countries.Many of these cases have been…

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