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First received: December 05, 2025

Clinical Trial: Hyaluronic Acid With Connective Tissue Grafting for Gingival Recession

Study Status: COMPLETED

Recruit Status: COMPLETED

Condition: Gingival Recession

Study Type: INTERVENTIONAL


Official Title: Clinical and Aesthetic Evaluation of Hyaluronic Acid in Addition to Connective Tissue Grafts in the Treatment of Gingival Recession Defects

Brief Summary: This study evaluates whether adding 0.8% hyaluronic acid (HA) to connective tissue grafting and coronally advanced flap surgery improves clinical and esthetic outcomes in the treatment of gingival recession. Adult patients with Miller I-II or Cairo RT1 recession defects will be randomly assigned to receive CTG alone or CTG with adjunctive HA. Mean root coverage at 6 months is the primary outcome, while secondary measures include gingival thickness, clinical attachment level, esthetic scores, postoperative…

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