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Impact of the lipid–inflammation axis on endometriosis risk: a multicenter case–control study using mediation analysis

Abstract: Endometriosis (EM) is often accompanied by dyslipidemia, but the causal relationship between dyslipidemia and inflammation remains unclear. This study aimed to explore…

Date: 2025-11-13

Association between urinary heavy metal mixtures and overactive bladder risk in the U.S. adult population: a cross-sectional study

Abstract: The existing body of literature consistently underscores the adverse health implications associated with exposure to toxic metals among humans. There is still a…

Date: 2025-11-13

Effects of nursing intervention based on the theory of planned behavior on visual function, blood sugar levels, and quality of life in perioperative patients with diabetic retinopathy

Abstract: To explore the impact of nursing intervention based on the Theory of Planned Behavior (TPB) on perioperative patients with diabetic retinopathy (DR). One hundred and…

Date: 2025-11-13

Development of a psychosocial-clinical nomogram to predict delayed medical help-seeking in women with stress urinary incontinence: a retrospective cohort study

Abstract: Delayed medical help-seeking is a common yet understudied behavior among women with stress urinary incontinence (SUI), potentially worsening symptom burden and…

Date: 2025-11-12

V.T.O.B.S.—Learning birth mechanics in virtual reality: a controlled cohort study in undergraduate medical education

Abstract: Virtual reality (VR) is increasingly applied in medical education to enhance learning and patient care. Teaching birth mechanics poses particular challenges, as students…

Date: 2025-11-12

Implementation of Nigeria's national surgical plan: building basic life support capacity to strengthen safe surgical care

Abstract: In many low- and middle-income countries (LMICs), including Nigeria, the burden of surgical conditions significantly contributes to morbidity and mortality rates.…

Date: 2025-11-12

Multi-antigen MVA-vectored SARS-CoV-2 vaccine, GEO-CM04S1, induces cross-protective immune responses to ancestral and Omicron variants

Abstract: The design focus of the first-generation COVID-19 vaccines was on the use of the SARS-CoV-2 spike (S) protein as the primary vaccine immunogen to induce high levels of…

Date: 2025-11-11

Promiscuous class II-binding SARS-CoV-2-nuc derived vaccine-peptide induced extensive conventional, innate and unconventional T cell responses

Abstract: We describe the T-cell response of two healthy SARS-CoV-2-unexposed volunteers to a SARS-CoV-2 nucleoprotein-derived vaccine peptide predicted to promiscuously bind…

Date: 2025-11-11

Global burden, trends, and inequalities in cancer and subtypes attributable to high BMI among older adults, 1990–2021: a secondary analysis of the global burden of disease study 2021

Abstract: High body mass index (BMI) is a significant modifiable risk factor for cancer, yet its global burden in older adults (aged ?60 years) remains incompletely understood.…

Date: 2025-11-11

Constrains for seeking perimenopausal healthcare services among women aged 40–60 years in Guangzhou, China: a cross-sectional study

Abstract: In China, the vast majority of perimenopausal healthcare (PMH) services are performed in a diversity of outpatient clinics, such that women may encounter more obstacles…

Date: 2025-11-11