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Machine learning prediction of feeding intolerance in preterm infants: a pre-feeding risk stratification model

Abstract: Feeding intolerance (FI) represents a prevalent and serious complication in preterm infants, contributing to delayed enteral nutrition, prolonged hospitalization, and…

Date: 2025-09-05

A novel homozygous frameshift mutation likely causing nonsense-mediated mRNA decay in an Algerian kindred with CD19 complex deficiency

Abstract: CD19 is an essential component of a membrane protein complex on B cells, which also includes complement receptor 2 (CD21), CD81, and CD225. It amplifies B cell receptor…

Date: 2025-09-05

Determining the diagnostic cut-off on the Chinese version of severity of dependence scale for DSM-5 stimulant use disorder

Abstract: To investigate the psychometric properties of the Chinese version of the Severity of Dependence Scale for stimulant (C-SDS-S) in screening for the DSM-5-defined…

Date: 2025-09-05

TBA-MLR score: a metabolic-immune prognostic biomarker for postoperative hepatocellular carcinoma

Abstract: To develop and validate a novel prognostic score combining serum total bile acid (TBA) and monocyte-to-lymphocyte ratio (MLR) for improved risk stratification in…

Date: 2025-09-05

Reduced spike specific T-cell responses in COVID-19 vaccinated subjects undergoing SARS-CoV-2 breakthrough infection

Abstract: T-cell responses to SARS-CoV-2 remain largely preserved across variants despite waning neutralizing antibodies. However, T-cell immunity may vary with the host’s immune…

Date: 2025-09-05

Correlation between blood urea nitrogen/albumin levels and 30-day all-cause mortality in critically Ill patients with heart failure: a retrospective cohort study and predictive model development based on machine learning

Abstract: The aim of this study was to investigate the correlation between blood urea nitrogen-albumin index (BAR) and 30-day and one-year all-cause mortality in patients with…

Date: 2025-09-05

Cost-effectiveness analysis of Chinese patent medicines for the treatment of postmenopausal osteoporosis in China

Abstract: Evidence indicates that Chinese patent medicines can significantly increase bone mass in patients with osteoporosis and alleviate symptoms associated with low bone…

Date: 2025-09-05

Suboptimal management of hypercholesterolemia in countries with high or very high cardiovascular risk: findings from the international DISCOVERY study

Abstract: The 2019 ESC/EAS guidelines introduced stricter low-density lipoprotein cholesterol (LDL-C) targets, particularly for patients at high and very high cardiovascular (CV)…

Date: 2025-09-05

Addressing sarcopenia management in primary care in Türkiye: gaps in the field and training needs of family physicians

Abstract: Sarcopenia is a current health threat that accompanies nutritional problems, cancers, and chronic diseases all around the world. Individuals in the risk group,…

Date: 2025-09-05

Evolutionary analysis of CD300A and CD300C paired receptors in primates

Abstract: The CD300 family comprises immunoglobulin superfamily receptors that regulate immune cell function through inhibitory or activating signals. CD300A and CD300C form a…

Date: 2025-09-05