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The role of LSR gene variants in early onset intrahepatic cholestasis: a case series with treatment options

Abstract: We report on three children with novel variants in the lipolysis-stimulated lipoprotein receptor ( LSR ) gene with clinical presentation with early onset intrahepatic…

Date: 2025-09-04

Perceptions and moral distress in surplus embryo disposition among Japanese IVF patients: a qualitative study

Abstract: The growing use of in vitro fertilization (IVF) in Japan has led to an increase in surplus frozen embryos and the associated ethical dilemmas. Cultural values,…

Date: 2025-09-04

Impact of anterior commissure invasion on the oncological efficacy of transoral laser microsurgery for T1 glottic cancer

Abstract: In glottic laryngeal cancer, anterior commissure (AC) involvement affects prognosis. T staging ignores AC subregion involvement and TNM staging may not suit as an AC…

Date: 2025-09-04

From trauma to trust: the initial psychometric evaluation of a survey instrument measuring trauma among transgender women in the US deep south

Abstract: Transgender women (TGW) experience unique life traumas that may perpetuate negative sexual health outcomes, such as high rates of HIV and sexually transmitted…

Date: 2025-09-04

Lessons from Ethiopian pharmaceutical regulation: a risk-based approach to overcome challenges and unlock opportunities

Abstract: Pharmaceutical products are essential for disease prevention, treatment, and public health promotion. With the rapid growth of the global pharmaceutical industry in…

Date: 2025-09-04

Advanced lung cancer inflammation index as a new predictor for colon cancer in elderly patients: an NHANES-based study

Abstract: Nutritional and inflammatory status have both been implicated in colon cancer risk. The advanced lung cancer inflammation index (ALI) is a composite prognostic index…

Date: 2025-09-04

Francisella tularensis -infected human neutrophils are trojan horses for infection of macrophages

Abstract: Francisella tularensis , the causative agent of tularemia, is a Gram-negative bacterium that infects neutrophils (polymorphonuclear leukocytes, PMNs) and macrophages.…

Date: 2025-09-04

Computed tomographic appearance of laryngeal lesions in 7 dogs

Abstract: To describe the computed tomographic (CT) features of neoplastic and inflammatory laryngeal masses. The authors hypothesized that specific CT features may help…

Date: 2025-09-04

The strengths, weaknesses, opportunities, and threats of generative artificial intelligence: a qualitative study of undergraduate nursing students

Abstract: While Generative Artificial Intelligence (Gen AI) is increasingly applied in nursing education, research on undergraduates’ perceptions, experiences, and impacts remains…

Date: 2025-09-04

Reliability and validity of the German version of the DePaul Symptom Questionnaire Post-Exertional Malaise (DSQ-PEM)

Abstract: This study aimed to examine the psychometric properties (reliability and validity) of a German version of the DSQ-PEM, using a representative sample from the German…

Date: 2025-09-04