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Clinical efficacy of minimally invasive transforaminal lumbar interbody fusion via bilateral channel for lumbar degenerative disease

Abstract: To evaluate the clinical efficacy of bilateral channel minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) in the management of lumbar degenerative…

Date: 2026-04-20

Current Status and influencing factors of adolescents’ awareness of functional gastrointestinal disorders and health education needs: a nationwide cross-sectional study

Abstract: Functional gastrointestinal disorders (FGIDs) are prevalent among teenagers, yet understanding of them is limited. This study aimed to evaluate adolescents’ awareness of…

Date: 2026-04-20

Endoscopic features associated with hospitalization outcomes in IgA vasculitis patients: a single-center retrospective cohort study

Abstract: To evaluate associations between endoscopic features and hospitalization outcomes in IgA vasculitis (IgAV) with gastrointestinal (GI) involvement, focusing on endoscopic…

Date: 2026-04-20

Caffeine-mediated CD39 + Treg activation via the CD39-adenosine receptor pathway is a novel risk factor for pulmonary tuberculosis

Abstract: The global impact of pulmonary tuberculosis (PTB) is compounded by a limited understanding of modifiable risk factors. While caffeine is the most consumed psychoactive…

Date: 2026-04-20

Probiotic-conditioned microbiota from preterm infants modulate immune response to pathogen challenge in a microbiota-humanized mouse model

Abstract: Early-life host-microbe interactions critically shape immune development, lifelong homeostasis, and disease susceptibility. The PRIMAL trial (Priming Immunity at the…

Date: 2026-04-20

Evaluation of dnDSA risk stratification using the updated PIRCHE-T2 model in two kidney transplant cohorts

Abstract: Development of de novo donor-specific antibodies (dnDSA) remains a key risk factor for antibody-mediated rejection and graft loss in kidney transplantation. The…

Date: 2026-04-20

Cytokine imbalance and immune network endotypes underlying heterogeneous response to omalizumab in chronic spontaneous urticaria

Abstract: Chronic spontaneous urticaria (CSU) exhibits marked immunologic heterogeneity, and a substantial proportion of patients show delayed or absent responses to anti-IgE…

Date: 2026-04-20

Non-invasive respiratory support attenuates lung damage in a murine model of bronchopulmonary dysplasia

Abstract: Bronchopulmonary dysplasia (BPD) is a chronic lung disease primarily affecting preterm infants exposed to prolonged oxygen therapy and mechanical ventilation. This study…

Date: 2026-04-20

Evaluation of unipolar and bipolar nanosecond pulses for calcium electrochemotherapy and immune response

Abstract: Calcium electrochemotherapy (CaECT) is an effective alternative to standard chemotherapeutic treatments, utilizing intracellular delivery of supraphysiological calcium…

Date: 2026-04-20

Limited immune perturbations in mice exposed to sustained low-dose ionizing radiation

Abstract: The effects of high-dose ionizing radiation (HDIR) exposure on the immune system are largely understood with consensus, yet there remains a fragmented understanding of…

Date: 2026-04-20