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Improving the specimen referral system in Ghana: findings from a landscape assessment

Abstract: Ghana's specimen referral system (SRS) is driven by vertical surveillance programs and outbreak response events; the lack of integration limits public health disease…

Date: 2025-09-02

Evaluating single nucleotide polymorphisms in beta - 2 - microglobulin – a theoretical study

Abstract: In Immunology, many molecules are composed of Immunoglobulin domains. Beta 2 Microglobulin (B2M) is the smallest Immunoglobulin Domain Superfamily member composed of a…

Date: 2025-09-02

Connecting with the community—experiences of medical students doing homestays in rural South Africa

Abstract: This study explores the educational and personal experiences of final-year medical students at the University of KwaZulu-Natal who participated in a homestay program…

Date: 2025-09-02

Gestational diabetes increases preterm membrane rupture risk through elevated hydroxydesmethylpiperine sulfate levels

Abstract: Gestational diabetes mellitus (GDM) is a metabolic disorder that increases the risk of premature rupture of membranes (PROM). The link between GDM-associated metabolic…

Date: 2025-09-02

Emotional coping strategies in children with and without special educational needs during the COVID-19 pandemic in Saudi Arabia

Abstract: The COVID-19 pandemic significantly disrupted children's daily lives, especially those of children with special educational needs and disabilities (SEND). This study…

Date: 2025-09-02

The efficacy of meditation on insula dysfunction in patients with chronic schizophrenia

Abstract: Meditation combined with antipsychotic medication can effectively improve the clinical symptoms and prognosis of patients with schizophrenia, but its underlying neural…

Date: 2025-09-02

Outcomes of descemet stripping automated endothelial keratoplasty for pediatric descemet membrane detachment with diffuse corneal edema

Abstract: To report Descemet stripping automated endothelial keratoplasty (DSAEK) outcomes for pediatric Descemet membrane detachment (DMD) with diffuse corneal edema. This study…

Date: 2025-09-02

TRP-related gene signatures predict survival and the immune microenvironment in rectal cancer: a comprehensive bioinformatics study

Abstract: The pathogenesis of rectal cancer (RC) involves a variety of biological mechanisms; however, the prognostic significance of temperature-sensitive receptor (TRP) channels…

Date: 2025-09-02

Developing models for the diagnosing of ulcerative colitis and prognosis of anti-TNF-? non-response based on neutrophil extracellular trap-associated genes

Abstract: Neutrophil extracellular traps (NET) play a pivotal role in the pathogenesis of ulcerative colitis (UC) and may contribute to the impaired response to anti-tumor…

Date: 2025-09-02

Malignant epithelia cells-derived spermine induces APOE+ macrophages to suppress tumor immunity in adenocarcinoma of the esophagogastric junction

Abstract: Adenocarcinoma of the esophagogastric junction (AEG) is increasingly recognized as a distinct gastrointestinal tumor type with a poor prognosis. However, the mechanisms…

Date: 2025-09-02