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Burden of malignant neoplasm of bone and articular cartilage from 1990 to 2021 and its predictions to 2030 in China compared with world

Abstract: To comprehensively examine the incidence and mortality of malignant neoplasms of bone and articular cartilage (MNBAC) in China compared with the world, as well as its…

Date: 2025-08-21

Rising tides of knee osteoarthritis: global trends and regional disparities among middle-aged and elderly populations from 1990 to 2021 and its prediction to 2035

Abstract: This study aims to analyze the global disease burden of knee osteoarthritis (KOA) among middle-aged and elderly populations (aged ?45 years) from 1990 to 2021, project…

Date: 2025-08-21

Antibodies against integrin ?v?6 have high diagnostic accuracy for ulcerative colitis

Abstract: Anti-integrin ?v?6 IgG autoantibodies showed good sensitivity and optimal specificity in ulcerative colitis (UC) compared to controls. We aim at confirming the…

Date: 2025-08-21

Development and validation of a nomogram model for prediction of dyslipidemia in children with Wilson disease: a retrospective analysis

Abstract: Wilson disease (WD), an inherited copper metabolism disorder, is linked to hepatic injury from copper accumulation-induced dyslipidemia. Children with WD have a high…

Date: 2025-08-21

Analysis of influencing factors and interaction effects on stroke recurrence in patients with middle cerebral artery occlusion treated with mechanical thrombectomy

Abstract: Stroke recurrence is an important factor affecting the prognosis of mechanical thrombectomy in patients with middle cerebral artery (MCA) occlusion. This study aims to…

Date: 2025-08-21

Prognostic significance of FT3 levels in hypertrophic cardiomyopathy patients with HFpEF

Abstract: This study sought to identify key prognostic factors in patients with hypertrophic cardiomyopathy (HCM) and heart failure with preserved ejection fraction (HFpEF),…

Date: 2025-08-21

Relationship between inflammatory markers and long-term prognosis in ICU patients with acute non-ST-segment elevation myocardial infarction

Abstract: This study aims to investigate the relation of inflammatory markers to the long-term prognosis of patients with severe non-ST-segment elevation myocardial infarction…

Date: 2025-08-21

Genotype clinical phenotype analysis of 35 cases of hereditary spherocytosis in children

Abstract: Hereditary spherocytosis (HS) is a common red blood cell membrane disease. It is currently clear that mutations in genes such as ANK1, SPTB, SPTA1, SLC4A1, EPB4.2 can…

Date: 2025-08-20

PD-L1 + neutrophils mediate immune regulation of CD8 + T cells in halo nevi

Abstract: Halo nevi are clinically common and are characterized by a circle of leukoderma around the central melanocytic nevus. Studies have shown that the pathogenesis of halo…

Date: 2025-08-20

Tofacitinib as an adjuvant treatment for pediatric Still's disease

Abstract: To describe the efficacy and safety of tofacitinib for pediatric Still's disease, also referred to as systemic-onset juvenile idiopathic arthritis (sJIA). Traditional…

Date: 2025-08-20