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Zoledronic acid and denosumab are associated with similar fracture incidence and mortality in patients with type 2 diabetes: a population-based cohort study

Abstract: To assess the comparative effectiveness of zoledronic acid vs . denosumab in prevention of major osteoporotic fractures and mortality among patients with type 2…

Date: 2025-08-04

The association between phenotypes of polycystic ovary syndrome and metabolic dysfunction-associated fatty liver disease

Abstract: Polycystic ovary syndrome (PCOS) is associated with an increased risk of non-alcoholic fatty liver disease (NAFLD). With the introduction of the new definition of…

Date: 2025-08-04

Increased mortality in patients with non-functioning pituitary tumors: a study in a tertiary center

Abstract: Most of the studies on mortality, survival analysis and predictor variables in patients with non-functioning pituitary adenomas (NFPA) are heterogeneous and limited; and…

Date: 2025-08-04

An interpretable machine learning approach for predicting drug-resistant epilepsy in children with tuberous sclerosis complex

Abstract: This study developed and validated an interpretable machine learning (ML) algorithm for predicting the risk of drug-resistant epilepsy (DRE) in children with Tuberous…

Date: 2025-08-04

A study on the distribution of interleukin-10 gene polymorphisms and their association with febrile seizure susceptibility in children from the Wenzhou region, Zhejiang Province

Abstract: Febrile seizures (FS) were the most common seizure disorder in young children, with a notable prevalence in the Zhejiang Province region of China. The pathogenesis of FS…

Date: 2025-08-04

The diagnostic value of lymphocyte profiling for infectious mononucleosis and mycoplasma pneumoniae pneumonia

Abstract: Infectious mononucleosis (IM) and mycoplasma pneumoniae pneumonia (MPP) are common pediatric diseases that can easily trigger immune responses. This study aims to detect…

Date: 2025-08-01

Case report of non-gene editing CD7 CAR T cell therapy in CD7 + Sézary syndrome: preclinical validation and first-in-human use

Abstract: Sézary syndrome (SS) is a leukemic form of cutaneous T cell lymphoma (CTCL), distinguished from mycosis fungoides by the presence of cancerous lymphocytes in the blood…

Date: 2025-08-01

Correlation study on the risk of cardiovascular adverse events in diabetic foot patients based on machine learning - a retrospective cohort study

Abstract: Diabetic Foot (DF), as a serious complication of diabetes, is closely related to major adverse cardiovascular events (MACE) and mortality. However, research on…

Date: 2025-08-01

Effects of high-dose vitamin D supplementation on bone mineral density in very low birth weight preterm infants

Abstract: Vitamin D deficiency is common among very low birth weight (VLBW) preterm infants due to challenges in achieving adequate enteral nutrition and reduced transplacental…

Date: 2025-08-01

The critical role of diet, exercise, and sleep in shaping the gut microbiota of children with idiopathic short stature: a Retrospective study

Abstract: To investigate the gut microbiota in children with varying degrees of idiopathic short stature (ISS) and to examine the relationship between their intestinal microbiota…

Date: 2025-08-01