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The effects of optic nerve sheath fenestration on visual function and OCT metrics in idiopathic intracranial hypertension: a retrospective study

Abstract: Idiopathic intracranial hypertension (IIH) is characterized by elevated intracranial pressure (ICP) without an identifiable cause and may lead to optic nerve damage and…

Date: 2026-03-26

Systemic metabolic dysfunction is associated with local treatment failure: the role of visceral adiposity index in anti-VEGF resistance in diabetic macular edema

Abstract: A substantial number of patients with diabetic macular edema (DME) exhibit resistance to standard anti-vascular endothelial growth factor (anti-VEGF) therapy,…

Date: 2026-03-26

Three-dimensional progressive correction of Madelung deformity using the Ilizarov technique in patients aged ?12 years: a retrospective study

Abstract: Madelung deformity is a rare developmental wrist abnormality that often leads to joint pain and limited mobility. Traditional surgical methods typically struggle to…

Date: 2026-03-26

Integrated stress response genes as novel biomarkers and therapeutic targets in ankylosing spondylitis: a transcriptomic and Mendelian randomization study

Abstract: Ankylosing spondylitis (AS) is a chronic inflammatory disorder with poorly defined pathogenic mechanisms. The integrated stress response (ISR), an evolutionarily…

Date: 2026-03-26

Analysis of risk factors for relapse in pediatric MOG antibody-associated disease: a single-center retrospective cohort study

Abstract: Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is an immune-mediated demyelinating disorder of the central nervous system. It has a higher…

Date: 2026-03-26

Efficacy and safety of adjunctive clobazam in Chinese patients with drug-resistant epilepsy: a single-center real-world study

Abstract: This study evaluated the efficacy and safety of adjunctive clobazam (CLB) in Chinese patients with drug-resistant epilepsy (DRE). We retrospectively included 121 DRE…

Date: 2026-03-26

Additive effect of patient anosognosia and theory of mind deficit on dementia caregiver distress

Abstract: Caregiver distress in dementia is multifactorial. The contribution of disease specific factors including anosognosia (poor awareness of cognitive/behavioral deficits)…

Date: 2026-03-26

The etiological spectrum of pediatric FUO and clinical management of PFAPA/SURF: a ten-year retrospective study

Abstract: This study aimed to define the etiologies and clinical features of pediatric Fever of unknown origin (FUO), focusing on periodic fever, aphthous stomatitis, pharyngitis,…

Date: 2026-03-26

Identification and validation of necroptosis-related genes in peripheral blood mononuclear cells of Sjögren disease

Abstract: Necroptosis has been implicated in multiple inflammatory and autoimmune disorders. However, its role in Sjögren disease (SjD) remains elucidated. In the current study,…

Date: 2026-03-26

A retrospective clinical analysis of pediatric mediastinal space-occupying lesions in a Chinese children’s hospital from 2015 to 2024

Abstract: Pediatric mediastinal space-occupying lesions (MSOLs) encompass a wide spectrum of conditions, including benign and malignant, infectious and reactive, as well as…

Date: 2026-03-25