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C-reactive protein to high-density lipoprotein cholesterol ratio: an independent risk factor for diabetic retinopathy in type 2 diabetes patients

Abstract: Background and objective: Diabetic retinopathy (DR) is associated with abnormal lipid metabolism and inflammation. However, a single lipid or inflammatory parameter…

Date: 2025-03-04

Interpreting clinical outcomes using different strut thickness in coronary artery disease: insights from vascular imaging analysis

Abstract: Background: Coronary artery disease is a global health concern that necessitates treatments, such as percutaneous coronary intervention (PCI) with drug-eluting stents…

Date: 2025-03-04

Phenotype and psychometric characterization of Phelan-McDermid syndrome patients: pioneering towards personalized medicine

Abstract: Introduction: Phelan-McDermid syndrome (PMS) is a genetic disorder caused by the loss of the terminal region of chromosome 22 or by pathogenic or likely-pathogenic…

Date: 2025-03-04

Assessment of commercially available artificial intelligence software for differentiating hemorrhage from contrast on head CT following thrombolysis for ischemic stroke

Abstract: Background: In patients who have undergone ischemic stroke therapy, retained iodine-based contrast can resemble acute intracranial hemorrhage (ICH) on standard computed…

Date: 2025-03-04

Integrative analysis of semaphorins family genes in colorectal cancer: implications for prognosis and immunotherapy

Abstract: Background: Semaphorins (SEMAs), originally identified as axon guidance factors, have been found to play crucial roles in tumor growth, invasiveness, neoangiogenesis,…

Date: 2025-03-04

Regulation of DNA methylation in lesional tissue of children with atopic dermatitis

Abstract: Background: Genetic and epigenetic mechanisms have been shown to play a role in the pathogenesis of atopic dermatitis (AD). However, the role of genes involved in the…

Date: 2025-03-03

Gut microbiota and other factors associated with increased T cell regulation in HIV-exposed uninfected infants

Abstract: Introduction: Infants exposed to HIV and uninfected (HEUs) are at higher risk of infectious morbidity than HIV-unexposed uninfected infants (HUUs). Multiple immune…

Date: 2025-03-03

Impact of family environment on mental disorders and quality of life in children with type 1 diabetes mellitus: a cross-sectional study and intervention policy analysis

Abstract: Background: Type 1 diabetes mellitus (T1DM) is common in adolescents and negatively affects their quality of life and mental health. This study examines the impact of…

Date: 2025-03-03