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Teprotumumab N01 for thyroid eye disease in China: clinical outcomes and quantitative MRI correlations

Abstract: Teprotumumab is an IGF-1R–targeted therapy for thyroid eye disease (TED). In routine practice, response assessment remains challenging and standardized imaging…

Date: 2026-03-20

Advancing neuro-ophthalmic diagnostics: a multimodal imaging approach integrating OCT angiography and AI-enhanced MRI for improved visual pathway analysis

Abstract: Recent advancements in neuro-ophthalmology necessitate integrative imaging methodologies to address the structural and functional complexities of the visual pathway.…

Date: 2026-03-20

Biomechanical evaluation of a novel L-shaped side-locking plate combined with OLIF: a finite element analysis considering 3 different bone densities

Abstract: Oblique lateral interbody fusion (OLIF) is a minimally invasive technique widely used for lumbar degenerative diseases. However, high rates of cage subsidence,…

Date: 2026-03-20

Performance evaluation of mainstream large language models in autoimmune hepatitis patient education: a comparative study of readability, quality, and reliability

Abstract: Autoimmune hepatitis (AIH) is a chronic immune-mediated liver disease that requires long-term management, in which effective patient education plays a critical role.…

Date: 2026-03-20

Leptin/Adiponectin Ratio as a new multidimensional biomarker in obese patients with liver steatosis undergoing VLEKT: results from a pilot study

Abstract: The Very-Low Energy-Ketogenic Therapy: (VLEKT) is an effective therapy for obesity and metabolic dysfunction, but the factors driving variability in the treatment…

Date: 2026-03-20

Minimally invasive percutaneous cannulated polyaxial screw and rod fixation thoracolumbar and lumbosacral vertebrae: cadaveric evaluation of accuracy and safety of a fluoroscopic-guided technique, in large breed dogs

Abstract: To develop and report the accuracy and safety of a technique for percutaneous pedicle screw-rod fixation of the thoracolumbar and lumbosacral regions using fluoroscopic…

Date: 2026-03-20

A multi-epitope approach for development of a universal vaccine against leptospirosis

Abstract: Leptospira , a zoonotic pathogen, poses a significant public health threat, causing morbidity and mortality in both humans and animals. Although several bacterin and…

Date: 2026-03-20

Alcohol consumption exacerbates high-fat diet-mediated disruptions in myelopoiesis and osteoclastogenesis in mouse models of metabolic dysfunction-associated liver diseases

Abstract: Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and Metabolic Dysfunction-Associated Alcohol-related Liver Disease (MetALD) exhibit systemic immune…

Date: 2026-03-20

Osteopontin from monocyte-derived dendritic cells mediates ozone-induced pulmonary responses in mice

Abstract: Asthma is a heterogeneous disease characterized by airway inflammation and hyperresponsiveness (AHR). Ozone, a common air pollutant, induces a neutrophilic phenotype of…

Date: 2026-03-19

Prognostic factors in Sézary syndrome - a retrospective propensity score-matched study on 1277 patients

Abstract: Sézary syndrome (SS) is a rare neoplasm associated with poor prognosis. Due to the rarity of the disease, large-scale investigations are scarce, while identifying…

Date: 2026-03-19