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Effect of propofol versus midazolam on short-term outcomes in patients with sepsis-associated acute kidney injury

Abstract: Background: Propofol and midazolam are commonly used sedative drugs in mechanically ventilated patients in the Intensive Care Unit (ICU). However, there is still a lack…

Date: 2024-09-06

Lipoprotein(a) as a novel biomarker for predicting adverse outcomes in ischemic heart failure

Abstract: Background: Lipoprotein(a) [Lp(a)] is an independent risk factor for atherosclerotic cardiovascular disease (ASCVD). However, the association between Lp(a) and adverse…

Date: 2024-09-05

Association between fatty liver index and cardiometabolic multimorbidity: evidence from the cross-sectional national health and nutrition examination survey

Abstract: Background: Metabolic dysfunction associated steatotic liver disease (MASLD) contributes to the cardiometabolic diseases through multiple mechanisms. Fatty liver index…

Date: 2024-09-05

Machine learning models for predicting risks of MACEs for myocardial infarction patients with different VEGFR2 genotypes

Abstract: Background: The development of prognostic models for the identification of high-risk myocardial infarction (MI) patients is a crucial step toward personalized medicine.…

Date: 2024-09-05

Type V collagen-induced nasal tolerance prevents lung damage in an experimental model: new evidence of autoimmunity to collagen V in COPD

Abstract: Background: Chronic obstructive pulmonary disease (COPD) has been linked to immune responses to lung-associated self-antigens. Exposure to cigarette smoke (CS), the main…

Date: 2024-09-05

Prevalence and significance of a canine bocavirus-2 outbreak in a cohort of military dogs in Austria

Abstract: Introduction: Bocaviruses are single-stranded DNA viruses from the Parvoviridae family, which have been minimally discussed in veterinary literature and are considered…

Date: 2024-09-05

Cardiovascular risk assessment using non-laboratory based WHO CVD risk prediction chart with respect to hypertension status among older Indian adults: insights from nationally representative survey

Abstract: Introduction: Knowledge of the risk of developing cardiovascular diseases (CVD) in the population is an important risk management strategy for the prevention of this…

Date: 2024-09-05

Risk factors for regional lymph node metastasis in rectal neuroendocrine tumors: a population-based study

Abstract: Introduction: The identification of risk factors for regional lymph node (r-LN) metastasis in rectal neuroendocrine tumors (R-NETs) remains challenging. Our objective…

Date: 2024-09-04

A phase III study to access the safety and efficacy of prolgolimab 250 mg fixed dose administered every 3 weeks versus prolgolimab 1 mg/kg every 2 weeks in patients with metastatic melanoma (FLAT)

Abstract: Background: Prolgolimab is the first Russian PD-1 inhibitor approved for the first-line treatment of unresectable or metastatic melanoma and advanced non-small cell lung…

Date: 2024-09-04