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Comparative safety profiles of baricitinib and tofacitinib in the treatment of adult alopecia areata: a pharmacovigilance study based on the FAERS database

Abstract: To provide a comparative overview of the post-marketing safety patterns of baricitinib and tofacitinib used for the treatment of adult alopecia areata (AA) by analyzing…

Date: 2026-01-12

Safety profile of vunakizumab in elderly patients with moderate-to-severe plaque psoriasis: a post-hoc analysis

Abstract: Elderly patients with moderate-to-severe plaque psoriasis are vulnerable to adverse events (AEs), which raise safety concerns in their management. This post-hoc analysis…

Date: 2026-01-12

Clinical and laboratory characteristics of hidradenitis suppurativa in a Chinese cohort: a retrospective analysis of 197 cases

Abstract: The clinical and laboratory characteristics of hidradenitis suppurativa (HS), particularly indicators related to disease severity, remain inadequately explored in Asian…

Date: 2026-01-12

The safety of high dose continuous propofol infusion in the pediatric intensive care unit at an academic medical center

Abstract: Adequate sedation is crucial in the care of critically ill children. Propofol, known for its rapid onset, reliable patient response, and short duration of action, offers…

Date: 2026-01-12

Deep learning-based optic nerve diameter sheath characterization and structure quantification on transorbital ultrasound images

Abstract: Optic nerve quantification plays a pivotal role as a biomarker in the non-invasive assessment of elevated intracranial pressure and other neuro-ophthalmic conditions.…

Date: 2026-01-12

Hypoxemia prediction model based on XGBoost during sedation for gastrointestinal endoscopy

Abstract: Hypoxemia is the most common complication of sedated gastrointestinal endoscopy and can lead to serious consequences. Predicting and preventing hypoxemia remains…

Date: 2026-01-12

Metabolic obesity phenotypes and risk of ischemic stroke: The Rural Chinese Cohort Study

Abstract: The association of metabolic obesity phenotypes and ischemic stroke remains controversial. We aimed to determine the risk of ischemic stroke according to metabolically…

Date: 2026-01-12

ATOMIC: a graph attention network for atopic dermatitis prediction using human gut microbiome

Abstract: Atopic dermatitis (AD) is a chronic inflammatory skin disease driven by complex interactions among genetic, environmental, and microbial factors; however, its etiology…

Date: 2026-01-08

Relationship between cognitive disengagement syndrome and headache in children: insights from biochemical markers

Abstract: This study aims to explore the possible relationship between Cognitive Disengagement Syndrome (CDS) and headaches in children and to understand the biochemical basis of…

Date: 2025-12-29

Prevalence of pedophilia in a forensic psychiatric population in Switzerland: a comparative study of contact vs non-contact and pedophilic vs non-pedophilic offenders

Abstract: Sexual offenses against minors represent a major public health and judicial concern. Pedophilia, defined as a persistent sexual preference for prepubescent children, is…

Date: 2025-12-29