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Patterns of response of breast cancer after neoadjuvant chemotherapy according to molecular subtype

Abstract: Neoadjuvant chemotherapy (NACT) is a key component in the treatment of locally advanced breast cancer, with pathologic complete response (pCR) varying by molecular…

Date: 2025-11-27

Machine learning-based prediction of response to Janus kinase inhibitors in patients with rheumatoid arthritis using clinical data

Abstract: Rheumatoid arthritis (RA) is a chronic inflammatory disease with considerable heterogeneity in treatment response, leaving many patients unable to achieve remission or…

Date: 2025-11-27

Predicting the risk of endometriosis in Chinese infertile women: development and assessment of a predictive nomogram

Abstract: This study aimed to establish a risk prediction model of endometriosis in infertile women and verify the model. A retrospective study was made of 140 infertile women…

Date: 2025-11-27

Post-traumatic stress disorder in French Guiana: prevalence and risk factors in the general population

Abstract: The context of French Guiana—characterized by frequent violence and intense immigration from regions where traumatic events are common—may lead to a different…

Date: 2025-11-27

Resistance evolution under potentiated sulphonamide pressure in Escherichia coli

Abstract: Antimicrobial resistance (AMR) poses an escalating global health threat. Potentiated sulphonamides are widely used in both veterinary and human medicine. This study…

Date: 2025-11-27

Vitamin D supplementation and its impact on leptin and interleukin-6 in women following religious intermittent fasting: a controlled study

Abstract: Vitamin D deficiency is highly prevalent in populations following intermittent or religious fasting, particularly Orthodox nuns with limited sun exposure and dietary…

Date: 2025-11-27

Socioeconomic status and motor coordination function among children with autism

Abstract: To examine the association of socioeconomic status with the motor coordination impairment (probable DCD) of autism in a Chinese population. Using cross-sectional data…

Date: 2025-11-27

Cross-species validation of a 6-miRNA blood signature for Parkinson’s disease: from MPTP mice to human PBMC and serum exosomes

Abstract: Early detection of Parkinson’s disease (PD) remains challenging due to the lack of reliable blood-based biomarkers. While microRNAs (miRNAs) show promise as circulating…

Date: 2025-11-27

Navigating barriers and facilitators to lifestyle changes after bariatric surgery among Emirati adolescents: a qualitative study

Abstract: Adolescent obesity is a major public health concern, with bariatric surgery emerging as an effective treatment option. However, little is known about adolescents’…

Date: 2025-11-27

Quantum AI for psychiatric diagnosis: enhancing dementia classification with quantum machine learning

Abstract: Early detection of dementia is a key requirement for effective patient management. Therefore, classification of dementia is pertinent and requires a highly accurate…

Date: 2025-11-27