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The predictive value of the pre-PCI prognostic nutritional index combined with the geriatric nutritional risk index for one-year outcomes in patients with chronic total occlusion

Abstract: Chronic total occlusion (CTO) is associated with high rates of major adverse cardiovascular and cerebrovascular events (MACCEs) after percutaneous coronary intervention…

Date: 2025-11-26

A machine learning algorithm to predict treatment effectiveness for Kawasaki disease in China: a retrospective model development and validation study

Abstract: Kawasaki disease (KD) is the primary cause of acquired heart disease in children. Intravenous immunoglobulin (IVIG) is the first-line therapy for KD; however, IVIG…

Date: 2025-11-26

Weight loss increases circadian gene expression and emotional well-being in individuals with obesity

Abstract: Obesity is associated with disruptions in circadian rhythms and emotional well-being that can contribute to metabolic and psychological health issues. This study aimed…

Date: 2025-11-26

The frequency of polycystic ovary syndrome in women with prediabetes compared with normoglycemic women

Abstract: To determine rate of polycystic ovary syndrome (PCOS) and its related features in women with prediabetes. Of 3465 consecutive women applied between 2021 and 2023, 3218…

Date: 2025-11-26

Barriers and facilitators to adopting health-promoting lifestyles in patients with psoriasis in China: a qualitative study using the COM-B and SEM

Abstract: Psoriasis is an inflammatory skin disease that places a heavy burden on patients and society. Lifestyle can affect the occurrence and progression of psoriasis and its…

Date: 2025-11-26

LL37-driven mast cell degranulation and inflammation in rosacea via TLR2/JAK2/STAT3 axis

Abstract: Rosacea is a chronic inflammatory facial dermatosis with incompletely elucidated pathogenesis. LL37 is a key molecular mediator in rosacea development, and mast cells…

Date: 2025-11-26

Recovery time and associated factors of severe acute malnutrition in children aged 0–59?months admitted to referral hospitals in Tanzania: an institution-based prospective cohort study

Abstract: Malnutrition represents a pervasive global health challenge that severely impacts individuals of all ages. In Tanzania, severe acute malnutrition (SAM) is a critical…

Date: 2025-11-26

Spillover effects of military healthcare reform on civilian hospitals in China

Abstract: Military hospitals in China served a dual role, providing substantial healthcare to civilians alongside their primary mission of supporting military personnel. The 2015…

Date: 2025-11-26

Osteocalcin in human breast milk over the course of lactation

Abstract: Breast milk is the best nutrition for newborns. Its composition is dynamic and adapted to the newborn’s individual needs. A variety of bioactive compounds, including…

Date: 2025-11-26

Supporting coach-led dual career guidance for student-athletes: validation of the web-based Japanese version of the dual career competency questionnaire for athletes

Abstract: The concept of a dual career, which emphasizes the integration of athletic and academic pursuits, has become increasingly central to athlete development policies…

Date: 2025-11-26