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Chronic hepatitis B and perioperative chemotherapy efficacy in colorectal liver metastases: an exploratory analysis of clinical and mechanistic evidence

Abstract: The optimal choice of chemotherapy regimen for resectable colorectal liver metastases (CRLM) is still undetermined. The study aimed to estimate the impact of…

Date: 2026-09-04

Transcatheter tricuspid valve replacement—a comparison of clinical and procedural outcomes of two different prostheses

Abstract: Transcatheter Tricuspid Valve Replacement (TTVR) has emerged as a treatment option for patients with severe tricuspid regurgitation (TR) who are at high surgical risk…

Date: 2026-09-04

Cardiac MRI-guided therapeutics in ischemic cardiomyopathy: impact on heart-team consensus and outcomes

Abstract: Our study aims to evaluate the influence of myocardial viability on therapeutic decision-making using cardiac MRI (CMR) and assess agreement and variability in…

Date: 2026-09-04

Exercise hemodynamics in adults with Fontan circulation assessed by noninvasive impedance cardiography

Abstract: Exercise intolerance is a hallmark of Fontan physiology despite preserved resting hemodynamics. The relative roles of stroke volume, chronotropic response, and vascular…

Date: 2026-09-04

Short-term mortality after intensive care admission in acute lymphoblastic versus predominantly acute myeloid leukemia: a retrospective cohort study using MIMIC-IV with eICU external replication

Abstract: Adults with acute leukemia admitted to intensive care have high early mortality. Whether acute lymphoblastic leukemia (ALL) adds prognostic information beyond baseline…

Date: 2026-09-03

Clinical and genomic characterization of KRAS G13X non-small cell lung carcinoma

Abstract: KRAS mutations (KRAS m )represent the most common oncogenic drivers in non–small cell lung cancer (NSCLC). However, molecular features and clinical implications of the…

Date: 2026-09-03

Direct visualization-guided endoscopic management of complex colonic diverticular disease: a proof-of-concept case series

Abstract: Complex colonic diverticular disease, including diverticular bleeding, inflammatory diverticular disease, presents substantial therapeutic challenges for conventional…

Date: 2026-09-03

The impact of chemoimmunotherapy on primary cold agglutinin disease and Waldenström macroglobulinemia-associated cold agglutinin syndrome

Abstract: Cold agglutinin-associated hemolysis (CAH) occurs in diverse clinical contexts, such as primary cold agglutinin disease (pCAD) and Waldenström…

Date: 2026-09-03

One trigger, two fates: hemolysate shapes neutrophil extracellular traps (NETs) formation in a context-dependent manner

Abstract: During systemic inflammation, neutrophil extracellular traps (NETs) capture pathogens but, in the long-term, can cause bystander damage to the vasculature. Another…

Date: 2026-09-03

Treatment and outcomes of hepatoblastoma in a tertiary care pediatric institution: a single-center experience

Abstract: Hepatoblastoma is the most prevalent pediatric malignant liver neoplasm, and despite substantial advances in multimodal treatment, outcome data from Southeast European…

Date: 2026-09-03