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Influence of metallic particles and TNF on the transcriptional regulation of NLRP3 inflammasome-associated genes in human osteoblasts

Abstract: Introduction: The release of mature interleukin (IL-) 1? from osteoblasts in response to danger signals is tightly regulated by the nucleotide-binding oligomerization…

Date: 2024-05-01

“A second birthday”? Experiences of persons with multiple sclerosis treated with autologous hematopoietic stem cell transplantation—a qualitative interview study

Abstract: Introduction and objective: Autologous hematopoietic stem cell transplantation (aHSCT) is a promising treatment option for persons with multiple sclerosis (pwMS).…

Date: 2024-05-01

Gestational hypothyroxinemia induces ASD-like phenotypes in behavior, proinflammatory markers, and glutamatergic protein expression in mouse offspring of both sexes

Abstract: Background: The prevalence of autism spectrum disorder (ASD) has significantly risen in the past three decades, prompting researchers to explore the potential…

Date: 2024-05-01

Daily-life stress reactivity and recovery following virtual-reality-based cognitive behavioral therapy in patients with a psychotic disorder

Abstract: Introduction: Studies have consistently demonstrated increased stress sensitivity in individuals with psychosis. Since stress sensitivity may play a role in the onset…

Date: 2024-04-30

Public perception of psychiatry, psychology and mental health professionals: a 15-year analysis

Abstract: Background: X (previously known as “Twitter”) serves as a platform for open discussions on mental health, providing an avenue for scrutinizing public perspectives…

Date: 2024-04-30

Evaluation of the Co–Go–Me angle as a predictor in Class II patients treated with Herbst appliance and skeletal anchorage: a retrospective cohort study

Abstract: Introduction: A condylion–gonion–menton (Co–Go–Me) angle threshold of 125.5° has been introduced as a predictive parameter of cephalometric mandibular response in the…

Date: 2024-04-30

Predictive biomarkers and initial analysis of maternal immune alterations in postpartum preeclampsia reveal an immune-driven pathology

Abstract: Introduction: Postpartum preeclampsia (PPPE) is an under-diagnosed condition, developing within 48 hours to 6 weeks following an uncomplicated pregnancy. The etiology of…

Date: 2024-04-30

PD-L1 targeted peptide demonstrates potent antitumor and immunomodulatory activity in cancer immunotherapy

Abstract: Background: In recent years, immunotherapy has been emerging as a promising alternative therapeutic method for cancer patients, offering potential benefits. The…

Date: 2024-04-30