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High vs. low tidal volume and pulmonary complications in patients with cervical spinal cord injury on mechanical ventilation: systematic review

Abstract: Introduction: Cervical spinal cord injury (CSCI) patients on mechanical ventilation often lack standardized guidelines for optimal ventilatory support. This study…

Date: 2024-03-27

Dietary survey of poultry egg intake among residents in Kunming city, southwest China

Abstract: Background: For almost all people, eggs can be a wholesome addition to the diet. However, there is insufficient applicable data to evaluate the poultry egg intake of…

Date: 2024-03-27

Untranslated regions (UTRs) are a potential novel source of neoantigens for personalised immunotherapy

Abstract: Background: Neoantigens, mutated tumour-specific antigens, are key targets of anti-tumour immunity during checkpoint inhibitor (CPI) treatment. Their identification is…

Date: 2024-03-27

Catatonia and melancholia interface: exploring a new paradigm for evaluation and treatment. A case series and literature review

Abstract: Background: Catatonia has been increasingly associated with mood disorders and is recognized as a specifier in the DSM-5 and DSM-5-TR. The DSM-5-TR recognizes…

Date: 2024-03-27

Intratumor tertiary lymphatic structure evaluation predicts the prognosis and immunotherapy response of patients with colorectal cancer

Abstract: Background: Immune checkpoint therapy, involving the programmed cell death 1 (PD-1) monoclonal antibody, has revolutionized the treatment of cancer. Tertiary lymphatic…

Date: 2024-03-27

Deep analysis of skin molecular heterogeneities and their significance on the precise treatment of patients with psoriasis

Abstract: Background: Psoriasis is a highly heterogeneous autoinflammatory disease. At present, heterogeneity in disease has not been adequately translated into concrete treatment…

Date: 2024-03-27

Associations of perchlorate, nitrate, and thiocyanate exposure with arthritis and inflammation indicators in young and middle-aged adults, NHANES 2005-2016

Abstract: Background: Perchlorates, nitrates, and thiocyanates are prevalent environmental chemicals. Their potential association with arthritis remains unexplored. This study…

Date: 2024-03-27

Staff perspectives on poor mental health in secondary school students: an increasing problem handled with insufficient resources

Abstract: Introduction: An increasing number of schools are recognizing the importance of addressing students' mental health based on the association with educational outcomes and…

Date: 2024-03-27

Comprehensive molecular and cellular characterization of endoplasmic reticulum stress-related key genes in renal ischemia/reperfusion injury

Abstract: Background: Renal ischemia-reperfusion injury (RIRI) is an inevitable complication in the process of kidney transplantation and lacks specific therapy. The study aims to…

Date: 2024-03-27

Efficacy of neuroendoscopic-assisted surgery in the management of symptomatic sacral perineural (Tarlov) cysts: a technical report

Abstract: Introduction: The Tarlov cysts are pathological enlargements of the cerebrospinal fluid spaces between the endoneurium and perineurium, which can cause intolerable…

Date: 2024-03-27