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Metformin potentiates arsenic disulfide in diffuse large B-cell lymphoma: modulation of BAX/BCL-2 apoptotic pathway and hedgehog pathway

Abstract: Arsenic disulfide (As 2 S 2 ) inhibits proliferation and induces apoptosis in diffuse large B-cell lymphoma (DLBCL) cells, its clinical application is constrained by…

Date: 2026-09-01

Effects of a “5?+?2” dietary management model on body composition and behavioral modification in Chinese children with obesity: a prospective, non-randomized controlled trial

Abstract: Continuous energy restriction may be associated with poor adherence and a risk of muscle mass loss in pediatric obesity management. This study evaluated the effects of a…

Date: 2026-09-01

Associations between household solid fuel use, kitchen ventilation, and depressive symptoms among older adults in China: a national cross-sectional study

Abstract: Household solid fuel use has been associated with adverse mental health outcomes among older adults. However, evidence on the association between household solid fuel…

Date: 2026-09-01

Associations of derived inflammatory, lipid, and anthropometric indices with CT-detected pulmonary nodules: a hospital-based cross-sectional study with explainable machine learning

Abstract: Pulmonary nodules are frequently detected during routine health-examination chest computed tomography (CT). From a systems-endocrinology perspective, routinely available…

Date: 2026-09-01

Social alienation among older adults with cognitive frailty: a latent profile analysis

Abstract: The rising prevalence of cognitive frailty among older adults necessitates a deeper understanding of its psychosocial consequences. Social alienation, a critical yet…

Date: 2026-09-01

Neutrophil-associated extracellular DNA pathways in vitiligo: compartment-specific changes following combined fractional CO 2 laser and NB-UVB therapy

Abstract: Vitiligo is a chronic inflammatory depigmenting skin disorder characterized by progressive loss of functional melanocytes, in which adaptive immune mechanisms,…

Date: 2026-09-01

A comparative study of short-term intensive and prolonged low-intensity simulation training on clinical competence among medical students

Abstract: Clinical simulation training is widely used to improve procedural proficiency and patient safety; however, the relative effectiveness of different training schedules…

Date: 2026-09-01

Nationwide analysis of medicine search behaviour and system performance: a one-year evaluation of MediVerify in Sri Lanka (July 2024–July 2025) based on 1.49 million search queries

Abstract: National-scale digital health platforms generate large volumes of usage data that provide insights into population-level healthcare needs. MediVerify, Sri Lanka's…

Date: 2026-09-01

Development and external validation of a metabolic and lipid-based model for predicting subsequent pregnancy in women with endometriosis

Abstract: Endometriosis is frequently associated with impaired fertility. Metabolic abnormalities and dyslipidemia may be relevant to reproductive dysfunction among women with…

Date: 2026-09-01

Evaluating the effectiveness of the geriatrician-designed “Older Patient Care and Seek Course” for family physicians

Abstract: The population is aging and many primary care providers report gaps in managing complex geriatric conditions. This study aims to evaluate the effectiveness of a six-hour…

Date: 2026-09-01