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Supplementary posterior fusion in patients operated on employing TLIF may decrease the instrumentation failure rate

Abstract: Background: It is supposed that additional posterior fusion may provide additional stability of the pedicle screw; however, the clinical impact of additional posterior…

Date: 2024-01-16

Changes in body mass index and waist circumference and heart failure in type 2 diabetes mellitus

Abstract: Background: To determine the association of unintentional changes in body mass index (BMI) and waist circumference (WC) with the risk of heart failure (HF) among adults…

Date: 2024-01-16

Neurosteroid [3?,5?]-3-hydroxy-pregnan-20-one enhances IL-10 production via endosomal TRIF-dependent TLR4 signaling pathway

Abstract: Background: Previous studies demonstrated the inhibitory effect of allopregnanolone (3?,5?-THP) on the activation of inflammatory toll-like receptor 4 (TLR4) signals in…

Date: 2024-01-16

The impact of prior SARS-CoV-2 infection on host inflammatory cytokine profiles in patients with TB or other respiratory diseases

Abstract: Background: Tuberculosis (TB) and COVID-19 are the two leading causes of infectious disease mortality worldwide, and their overlap is likely frequent and inevitable.…

Date: 2024-01-16

Development and internal validation of a novel predictive model for SDHB mutations in pheochromocytomas and retroperitoneal paragangliomas

Abstract: Aim: To develop and internally validate a novel predictive model for SDHB mutations in pheochromocytomas and retroperitoneal paragangliomas (PPGLs).

Date: 2024-01-16

Gemtuzumab ozogamicin for relapsed or primary refractory acute myeloid leukemia in children—the Polish Pediatric Leukemia and Lymphoma Study Group experience

Abstract: Background: Gemtuzumab ozogamicin (GO), one of the first targeted drugs used in oncology, consists of an anti-cluster of differentiation 33 (CD33) monoclonal antibody…

Date: 2024-01-16

Impact of the baseline insulin resistance surrogates and their longitudinal trajectories on cardiovascular disease (coronary heart disease and stroke): a prospective cohort study in rural China

Abstract: Background: This study aimed to assess the association of baseline insulin resistance (IR) surrogates and their longitudinal trajectories with cardiovascular diseases…

Date: 2024-01-16