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High-grade synovitis associates with clinical markers and response to therapy in chronic inflammatory arthritis: post hoc analysis of a synovial biomarkers prospective cohort study

Abstract: Background: Inflammatory arthritis (IAs), such as rheumatoid arthritis (RA) and psoriatic arthritis (PsA), are characterized by the presence of chronic synovitis. The…

Date: 2024-01-11

Ankylosing spondylitis: acute/subacute vs. chronic iridocyclitis - a bidirectional two-sample Mendelian randomization study

Abstract: Background: Observational studies found associations between ankylosing spondylitis (AS) and iridocyclitis (IC), but the causality remained unconfirmed.

Date: 2024-01-11

Exercise therapy for knee osteoarthritis pain: how does it work? A study protocol for a randomised controlled trial

Abstract: Introduction Muscle strengthening training (MST) and behavioural graded activity (BGA) show comparable effects on knee osteoarthritic (KOA) pain, but the mechanisms of…

Date: 2024-01-10

Predictive factors for the treatment success of peri-implantitis: a protocol for a prospective cohort study

Abstract: Introduction Peri-implantitis, a common biological complication of dental implant, has attracted considerable attention due to its increasing prevalence and limited…

Date: 2024-01-10

Psychometric properties of the living with long term conditions scale in an English-speaking population living with long term conditions in the UK

Abstract: Objective To present the psychometric properties of the living with long-term condition (LwLTCs) scale in an English-speaking population of people with different LTCs.…

Date: 2024-01-10

Integrating 4 methods to evaluate physical function in patients with cancer (In4M): protocol for a prospective cohort study

Abstract: Introduction Accurate, patient-centred evaluation of physical function in patients with cancer can provide important information on the functional impacts experienced by…

Date: 2024-01-10

Comparing the efficacy and safety of three surgical approaches for total hysterectomy (TSATH): protocol for a multicentre, single-blind, parallel-group, randomised controlled trial

Abstract: Introduction Hysterectomy is the most common surgical procedure in the field of gynaecology. The traditional multiport laparoscopy, transumbilical laparoendoscopic…

Date: 2024-01-10

Wearables for early detection of atrial fibrillation and timely referral for Indigenous people ?55 years: mixed-methods protocol

Abstract: Introduction Digital health technologies have the potential to provide cost-effective care to remote and underserved populations. To realise this potential, research…

Date: 2024-01-10