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PGT-A versus expectant management for fertile patients with recurrent pregnancy loss and prior aneuploidy: a dual-center, real-world study of 5-year cumulative pregnancy outcomes

Abstract: This study evaluated the effectiveness and cost-effectiveness of preimplantation genetic testing for aneuploidy (PGT-A) versus expectant management (EM) for achieving…

Date: 2026-08-27

Pre-treatment serum phosphate as a metabolic correlate of live birth after IVF/ICSI: a retrospective cohort study

Abstract: Oocyte developmental competence is influenced by the systemic metabolic milieu during folliculogenesis. Inorganic phosphate is essential for ATP synthesis, nucleic acid…

Date: 2026-08-27

Association of atherogenic index of plasma and its modified indices with gestational diabetes mellitus: a prospective cohort study based on the Korean population

Abstract: Gestational diabetes mellitus (GDM) is a common pregnancy complication, yet current diagnosis at 24–28 weeks may occur after metabolic changes have already begun. The…

Date: 2026-08-27

Machine learning prediction of adverse events during minutes 15–30 of recovery in patients event-free at 15?min after sedated gastrointestinal endoscopy

Abstract: Sedated gastrointestinal (GI) endoscopy is widely used for diagnosis and treatment but may be complicated by respiratory and hemodynamic adverse events (AEs) during…

Date: 2026-08-27

A high-risk sepsis subtype identified by regulated cell death signatures and MAD2L2 validation

Abstract: Regulated cell death (RCD) is closely involved in immune dysregulation and organ injury during sepsis, yet the coordinated transcriptional features of multiple RCD…

Date: 2026-08-27

Day-4 antipseudomonal and anti-MRSA de-escalation was not associated with higher mortality in critically ill patients with sepsis

Abstract: Broad empiric antibiotics are often appropriate at the start of intensive care unit (ICU) sepsis care; however, continued antipseudomonal or anti-methicillin-resistant…

Date: 2026-08-27

Chelidonic acid ameliorates Aspergillus fumigatus keratitis via antifungal and anti-inflammatory activities

Abstract: This study aimed to evaluate the therapeutic efficacy of chelidonic acid (CA) in Aspergillus fumigatus ( AF )-induced keratitis and to elucidate the underlying molecular…

Date: 2026-08-27

Aggregate index of systemic inflammation and glaucoma status: population-based evidence with clinical validation

Abstract: Glaucoma is a major cause of irreversible visual impairment, but evidence on the association between the aggregate index of systemic inflammation (AISI) and glaucoma…

Date: 2026-08-27

Impact of COVID-19 on corneal endothelial density and morphology: a cross-sectional study in convalescent patients

Abstract: This study aimed to investigate the effect of COVID-19 infection on corneal endothelial cell density and morphology, and to analyze the related factors. This…

Date: 2026-08-27

Transcriptome-based profiling of programmed cell death signatures identifies two osteoarthritis subtypes and the hub gene DNM1L

Abstract: Osteoarthritis (OA) poses a significant global health risk, with programmed cell death (PCD) playing a key role in its development. This study utilized integrated…

Date: 2026-08-27