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Association of cumulative remnant cholesterol exposure with adverse outcomes after PCI in acute ST-segment elevation myocardial infarction

Abstract: Remnant cholesterol (RC) has been associated with adverse cardiovascular outcomes; however, the relationship between cumulative RC exposure and clinical outcomes after…

Date: 2026-08-26

Contrasting relapse rate associated with the absence of HLA-A3/A11 in T cell-replete haploidentical transplantation

Abstract: Natural killer cell alloreactivity contributes to the graft-versus-leukemia (GVL) effect of haploidentical hematopoietic stem cell transplantation (haplo-HSCT). However,…

Date: 2026-08-25

Ficoll-based isolation biases the profiling of immune cells and leukemic blasts in AML samples

Abstract: An increasing number of studies focus on anti-tumor immune responses. In acute myeloid leukemia (AML), blasts and immune cells, such as T cells, are frequently studied…

Date: 2026-08-25

Serum copeptin predicts atrial fibrillation recurrence and is associated with increased all-cause mortality

Abstract: Copeptin, a stable surrogate marker of arginine vasopressin, reflects neurohumoral activation and hemodynamic stress. Its prognostic value in heart failure is…

Date: 2026-08-25

Enhanced sialylation of bone marrow mesenchymal stromal cells contributes to immune remodeling through macrophage polarization in multiple myeloma patients

Abstract: In multiple myeloma (MM), the immune system is disrupted, partly due to tumor-modified bone marrow mesenchymal stromal cells (BM-MSCs). These MSCs show altered…

Date: 2026-08-25

Polish translation and validation of the student satisfaction and self-confidence in learning scale among healthcare students at the Pomeranian Medical University in Szczecin: a single-center cross-sectional validation study

Abstract: Simulation-based education is an established component of healthcare training, yet robust Polish-language instruments for evaluating the learner’s reaction to simulation…

Date: 2026-08-25

Hypertension identified in early adulthood as an endocrine–vascular risk factor for uterine fibroids in reproductive-age women: a nationwide cohort study

Abstract: The association between hypertension identified in early adulthood and uterine fibroid development in young women remains poorly understood. Therefore, we aimed to…

Date: 2026-08-25

Cardiac and systemic biological age capture complementary aging signals associated with cardiovascular disease

Abstract: Biological ages capture aging signatures associated with aging-related outcomes, but most models use systemic and unimodal indices. The added value of organ-specific and…

Date: 2026-08-25

Low-dose allergen targeting to cDC2 induces long-term protection associated with induction of regulatory-like IL-10 + Foxp3 - CD8 + T cells in mice

Abstract: The prevalence of allergic diseases is rising worldwide. Desensitizing immunotherapy is currently the only available treatment, but it is often ineffective for certain…

Date: 2026-08-25

Neutrophil extracellular trap-associated responses are associated with tissue factor expression and coagulation abnormalities during anaphylaxis

Abstract: Anaphylaxis is a severe, fast-onset hypersensitivity reaction. Studies have shown that neutrophils play an important role in the acute phase of anaphylaxis. Activated…

Date: 2026-08-25