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Comparative performance of contemporary multimodal large language models in retinal imaging question answering

Abstract: Contemporary multimodal large language models (LLMs) can process both clinical text and medical images, but their reliability in retinal imaging-based question answering…

Date: 2026-08-20

Impact of diagnosis-related group–based bundled payment on hospitalization costs and clinical outcomes in total hip arthroplasty: an interrupted time series analysis from Wenzhou, China

Abstract: China's nationwide rollout of diagnosis-related group (DRG) bundled payment, implemented from January 2021, is one of the most consequential structural reforms to…

Date: 2026-08-20

TiRobot-assisted cannulated screw fixation for calcaneal fractures: a meta-analysis of surgical trauma, anatomical restoration, and functional recovery

Abstract: TiRobot-assisted cannulated screw fixation may improve surgical precision and clinical outcomes in calcaneal fractures. This meta-analysis evaluated its effects on…

Date: 2026-08-20

Multi-omics analysis identifies fibroblast IGFBP5 as a key target of anti-TNF? therapy in ulcerative colitis

Abstract: Resistance to anti-TNF? therapy (e.g., infliximab) in ulcerative colitis (UC) remains a significant clinical challenge, with the underlying cellular and spatial…

Date: 2026-08-20

Washed microbiota transplantation is associated with Helicobacter pylori -negative conversion and circulating group 2 innate lymphoid cell profiles

Abstract: Antibiotic resistance remains a major challenge in the management of Helicobacter pylori ( H. pylori ) infection. Microbiota-based interventions, including washed…

Date: 2026-08-20

Documented inpatient aspirin use and in-hospital mortality in non-HIV tuberculous meningitis: a propensity score-weighted retrospective cohort study

Abstract: Aspirin has antiplatelet and anti-inflammatory effects that may be relevant to cerebrovascular complications of tuberculous meningitis (TBM), but its association with…

Date: 2026-08-20

Pre-treatment T cell features and immune-milieu characteristics shape treatment-induced exhaustion and resistance to Blinatumomab in B-cell acute lymphoblastic leukemia

Abstract: Blinatumomab (Blina), a CD19×CD3 bispecific T cell engager, is approved for the treatment of B-cell precursor acute lymphoblastic leukemia (BCP-ALL), yet resistance…

Date: 2026-08-20

Longitudinal immune profiling demonstrates persistent MAIT cell reduction and temporal cytokine alterations after aneurysmal subarachnoid hemorrhage

Abstract: Neuroinflammation and systemic immune dysregulation are increasingly recognized as key contributors to secondary brain injury after aneurysmal subarachnoid hemorrhage…

Date: 2026-08-20

UBA1 enhances phagocytosis by suppressing CD47 expression in small cell lung cancer

Abstract: Small cell lung cancer (SCLC) exhibits a limited overall response rate to immunotherapy, largely due to its highly immunosuppressive microenvironment. CD47, an innate…

Date: 2026-08-20

Exploring medication adherence and risk factors in elderly patients with hepatocellular carcinoma undergoing oral targeted therapy: a cross-sectional observational study

Abstract: Oral targeted therapy is now integral to the management of older adults with hepatocellular carcinoma (HCC), yet suboptimal adherence persistently undermines its…

Date: 2026-08-20