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Repulsive guidance molecule-a regulates neutrophil-associated Th17 responses in CNS autoimmunity

Abstract: Repulsive guidance molecule-A (RGMa) is well-known for its roles in T-cell-mediated neuroinflammation and CNS repair. Innate-adaptive immune interactions, particularly…

Date: 2026-08-19

Clinical phenotype spectrum and prognostic analysis of DNM1L- related disorders: a single-center cohort study of 18 patients

Abstract: To summarize the clinical and genetic characteristics of DNM1L -related disorders and explore genotype-phenotype correlations and prognosis. We retrospectively analyzed…

Date: 2026-08-19

Changes in serum sodium during an external ventricular drain weaning in patients with subarachnoid hemorrhage

Abstract: Dysnatremia is a common complication following non-traumatic subarachnoid hemorrhage (SAH). Potential causes include induced hypernatremia and hyponatremia related to…

Date: 2026-08-19

A clinical evaluation of HyperSight CBCT enhanced offline adaptive breast radiotherapy

Abstract: Anatomical changes such as seroma shrinkage, soft-tissue deformation, and tumor-bed displacement frequently occur during breast radiotherapy and may compromise target…

Date: 2026-08-19

Assessing the health outcomes, productivity gains, and budget impact of anti-PD-(L)1’s in the early stages of cancer treatment in Greece

Abstract: Cancer incidence and mortality have been increasing both globally and in Greece. The aim of this study was to quantify the health benefits and budget impact of including…

Date: 2026-08-19

Unlocking HER2 as a target in KRAS-mutated rectal cancer: a case of significant response to zanidatamab-based regimen

Abstract: Colorectal cancer (CRC) with human epidermal growth factor receptor 2 (HER2) overexpression and RAS mutations is often associated with poor response to conventional…

Date: 2026-08-19

Single-fraction stereotactic radiotherapy for lung malignancies: preliminary results of a mono-institutional experience

Abstract: The use of stereotactic body radiotherapy for primary and secondary lung lesions is well established. Although being supported by international guidelines, the…

Date: 2026-08-19

A real-world multicenter study on postoperative adjuvant treatment patterns and prognostic implications following neoadjuvant immunochemotherapy for esophageal squamous cell carcinoma

Abstract: With the widespread application of neoadjuvant immunochemotherapy (nICT) in locally advanced resectable esophageal squamous cell carcinoma (ESCC), determining the…

Date: 2026-08-19

Clinicopathological characteristics and response to neoadjuvant chemotherapy in HER2-low hormone receptor-positive breast cancer: a retrospective cohort study

Abstract: HER2-low breast cancer constitutes a substantial proportion of hormone receptor-positive (HR+) cases, yet its biological behavior and responsiveness to neoadjuvant…

Date: 2026-08-19

Associations between uncertainty in illness and cardiac rehabilitation adherence in patients with CHD: a cross-sectional chain mediation and latent profile analysis of cardiac self-efficacy and fear of activity

Abstract: This study aimed to integrate variable-centered and person-centered approaches to examine the relationship between uncertainty in illness and cardiac rehabilitation…

Date: 2026-08-19