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Micromegaly: a distinct clinical entity? Insights from a monocentric cohort study

Abstract: The term “micromegaly” historically refers to patients with acromegalic features, elevated IGF-1, but normal growth hormone (GH) levels. The physiological mechanism, the…

Date: 2026-07-20

IgE levels correlate with Fc ? RI expression on circulatory basophils but not with their activation response in patients with Hymenoptera anaphylaxis

Abstract: Measurement of IgE levels, skin prick tests (SPT), and basophil activation tests (BAT) are the gold standards for diagnosing Hymenoptera allergy. Currently, BAT most…

Date: 2026-07-20

RAG1 deficiency durably alters dermal group 2 innate lymphoid cells and modifies contact hypersensitivity

Abstract: Dermal group 2 innate lymphoid cells (dILC2s) contribute to skin homeostasis and inflammatory responses, yet they are frequently studied in Rag1-deficient mice in which…

Date: 2026-07-20

Risk factors and a nomogram for predicting severe acute kidney injury in pediatric sepsis: a retrospective study

Abstract: To develop and validate a nomogram for predicting the risk of severe acute kidney injury (AKI) in children with sepsis. A total of 987 children with sepsis admitted to…

Date: 2026-07-20

Gram-negative bloodstream infections in pediatric patients: antimicrobial resistance and factors associated with mortality

Abstract: Gram-negative bloodstream infections (BSIs) are associated with substantial morbidity and mortality in pediatric patients, particularly among critically ill children.…

Date: 2026-07-20

Association of serum growth differentiation factor 11 with asthma severity, inflammation, and airway remodeling in pediatric patients

Abstract: Growth differentiation factor 11 (GDF11), a member of the transforming growth factor beta (TGF- ? ) superfamily, is implicated in tissue remodeling and inflammation.…

Date: 2026-07-20

Integrated cardiac, endocrine, and genetic assessment in adolescent basketball players

Abstract: Athletes pursuing a professional basketball career are routinely evaluated by sports physicians using laboratory testing, electrocardiography, and exercise stress…

Date: 2026-07-20

IgA anti-?2-glycoprotein I as an independent risk factor in acute venous thromboembolism

Abstract: Venous thromboembolism (VTE) is the third most common cause of cardiovascular death. Primary Antiphospholipid Syndrome (P-APS) is a chronic systemic autoimmune disorder…

Date: 2026-07-20

An interpretable machine-learning model for early prediction of acute kidney injury in polytrauma patients

Abstract: Acute kidney injury (AKI) is a frequent and clinically important complication after polytrauma, but early risk stratification remains challenging because conventional…

Date: 2026-07-20

Course-specific performance and mentor characteristics in an undergraduate tutorial system in medical education

Abstract: Mentorship programs are widely used in medical education, but evidence linking specific mentor characteristics to students’ course-specific theoretical performance…

Date: 2026-07-20