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TLR25 is endosomally located and responds to Francisella infection in Atlantic cod

Abstract: Atlantic cod possess a unique immune system due to the loss of the MHC II antigen-presenting system and an extreme expansion of the MHC class I repertoire. Additional…

Date: 2026-07-08

Associations of parathyroid hormone and atrial fibrillation: epidemiological insights from the LURIC study

Abstract: Parathyroid hormone (PTH) influences calcium handling in cardiomyocytes and sympathetic cardiac signaling. It has been linked to arterial hypertension and cardiovascular…

Date: 2026-07-08

Prognostic value of baseline 18 F-FDG PET/CT metabolic parameters in EGFR-mutant lung adenocarcinoma patients treated with EGFR-TKIs

Abstract: To investigate the correlation between baseline 1 ?F-FDG PET/CT metabolic parameters and progression-free survival (PFS) in EGFR-mutant lung adenocarcinoma receiving…

Date: 2026-07-08

Prognostic significance of continuing immunotherapy beyond progression in unresectable lung adenocarcinoma

Abstract: In patients with unresectable lung adenocarcinoma, whether cross-line immunotherapy (CIT) can improve clinical outcomes remains unclear. This study enrolled patients…

Date: 2026-07-08

Multidimensional profile of functional cognitive disorders: the experience of the memory clinic in Abidjan, Côte d’Ivoire, sub-Saharan Africa

Abstract: Functional cognitive disorders (FCD) are increasingly recognized but underdiagnosed. In sub-Saharan Africa, the topic is rarely discussed and the data is unknown. The…

Date: 2026-07-08

Validation of the CONSULT-PSYCHIATR Scale: reasons for reluctance to seek psychiatric consultation among workers in Peru

Abstract: Workers may be reluctant to attend psychiatric consultation because of stigma, interpersonal concerns, and practical barriers. In Peru, brief instruments specifically…

Date: 2026-07-08

Correcting depressed distal radial malunions at distal levels via a 5?mm incision

Abstract: This study aims to evaluate the efficiency of correcting depressed distal radial malunions at distal levels via a 5?mm incision. Between May 2021 and October 2023, 46…

Date: 2026-07-08

Comparative treatment persistence of upadacitinib vs. tofacitinib in psoriatic arthritis: a multicenter observational study from the BIRRA cohort

Abstract: Real-world comparative data on treatment persistence of upadacitinib and tofacitinib in psoriatic arthritis remain limited. Because persistence reflects treatment…

Date: 2026-07-08

Clinical characteristics and risk factors of atrial fibrillation detection after acute ischemic stroke

Abstract: The atrial fibrillation detected after stroke (AFDAS) confers an elevated risk of unfavorable outcomes for acute ischemic stroke (AIS) patients, necessitating early…

Date: 2026-07-08

Cytokeratin-18 increase as a signal for early liver cell changes in high-fat diet-induced obesity before overt steatohepatitis

Abstract: The major cause of non-alcoholic fatty liver disease (NAFLD) is obesity; in fact, this condition has been defined as metabolic dysfunction-associated steatotic liver…

Date: 2026-07-08