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Development and validation of an interpretable machine learning model for predicting atrial fibrillation risk in middle-aged and older patients with coronary heart disease

Abstract: Coronary heart disease (CHD) and atrial fibrillation (AF) frequently coexist, yet existing risk stratification tools inadequately capture the nonlinear, multidimensional…

Date: 2026-07-08

The association between C-reactive protein-triglyceride glucose index and all-cause mortality in patients with cardiovascular-kidney-metabolic syndrome: a single-center retrospective cohort study

Abstract: Patients with cardiovascular-kidney-metabolic (CKM) syndrome have high mortality risk. The C-reactive protein–triglyceride glucose index (CTI) integrates inflammation…

Date: 2026-07-08

Glofitamab in the sequential treatment of relapsed/refractory B-Cell lymphoma: a single-center real-world study

Abstract: Glofitamab is a bispecific antibody (BsAb), and has good efficacy in relapsed or refractory B-cell non-Hodgkin lymphoma (r/r B-NHL), especially in relapsed/refractory…

Date: 2026-07-07

Modified-release hydrocortisone (Efmody ® ) in children with congenital adrenal hyperplasia: a retrospective registry study

Abstract: Replacement therapy for congenital adrenal hyperplasia (CAH) in childhood includes hydrocortisone and, in salt-wasting forms, addition of fludrocortisone.…

Date: 2026-07-07

Inverse association of circulating kallikrein-related peptidase 7 with renal function and mortality risk in patients with chronic kidney disease

Abstract: Kallikrein-related peptidase 7 (KLK7) is a protease implicated in metabolic disease and obesity. Patients with chronic kidney disease (CKD) exhibit several…

Date: 2026-07-07

Diagnostic utility of the insulin-to-C-peptide molar ratio in differentiating insulin autoimmune syndrome and exogenous insulin antibody syndrome from insulinoma

Abstract: Although an insulin-to-C-peptide molar ratio greater than 1 has traditionally been considered suggestive of insulin autoimmune syndrome (IAS), its diagnostic value…

Date: 2026-07-07

Development and validation of a nomogram for predicting peripheral atherosclerosis in early-stage type 2 diabetic kidney disease: a retrospective hospital-based study

Abstract: Microvascular disease is a common complication of type 2 diabetes mellitus (T2DM). As a typical microvascular complication, diabetic kidney disease (DKD) interacts with…

Date: 2026-07-07

Reconstruction of large truncal defects post-malignant tumor excision using triple rhomboid flaps

Abstract: The reconstruction of large defect after skin malignant tumor excision is a challenge in dermatologic surgery and reconstructive surgery. This study describes the use of…

Date: 2026-07-07

Profile-associated financial and access-related framing in LLM-generated pediatric asthma referral plans: a factorial audit of seven large language models

Abstract: Large language models (LLMs) are increasingly considered for clinical documentation, referral support, and patient-facing communication. Biomedical accuracy alone may be…

Date: 2026-07-07

Alanine aminotransferase elevation in hospitalized children with infectious mononucleosis: independent associations with Epstein–Barr virus DNA load, age, and sex

Abstract: Alanine aminotransferase (ALT) elevation is common in pediatric infectious mononucleosis, but its relationship with Epstein–Barr virus (EBV) DNA load, age, and sex…

Date: 2026-07-07