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Factors associated with relapse/progression in pediatric trunk and extremity rhabdomyosarcoma

Abstract: Rhabdomyosarcoma (RMS) of the trunk and extremities is associated with unfavorable outcomes due to high rates of metastasis and relapse. However, large-scale studies…

Date: 2026-07-02

Adult weight change across the life course and cardiovascular disease prevalence and mortality: a population-based study

Abstract: Associations between long-term adult weight change and cardiovascular disease (CVD) risk remain incompletely understood, especially regarding life-stage-specific…

Date: 2026-07-02

Analytical agreement and clinical interchangeability of routine complete blood count parameters between the Atellica HEMA 580 and Sysmex XN-1000 analyzers: a CLSI EP09c study

Abstract: Analytical consistency in complete blood count (CBC) testing is essential when introducing new hematology analyzers into routine clinical use. This study evaluated the…

Date: 2026-07-02

Steroid alterations in Cushing’s disease persist after remission: ACTH-driven steroid changes dissociate from mood-regulatory neurosteroids

Abstract: Cushing’s disease (CD) is associated with high rates of depression and anxiety that often persist despite biochemical remission, yet the underlying mechanisms remain…

Date: 2026-07-02

Cellular interaction of mycosis fungoides tumor cells changes from cytotoxic CD8+ T cells in plaques to B cells in tumors

Abstract: Mycosis Fungoides (MF) is characterized by the proliferation of malignant skin-homing memory CD4+ T cells. The disease typically follows an indolent course, progressing…

Date: 2026-07-02

Cardiovascular safety and early myocardial deformation signal after upadacitinib initiation in immune-mediated inflammatory disorders

Abstract: Janus kinase (JAK) inhibitors are approved for several immune-mediated inflammatory disorders (IMIDs), but regulatory agencies, including the European Medicines Agency…

Date: 2026-07-02

Association between heavy metals, essential trace elements in follicular fluid and diminished ovarian reserve: a hospital-based case-control study

Abstract: To investigate the distribution of heavy metals and essential trace elements in follicular fluid (FF) and their association with diminished ovarian reserve (DOR) using a…

Date: 2026-07-02

Blood-activating, depression-relieving formula alleviates post-stroke depression: mechanistic insights from network pharmacology and microglial validation

Abstract: Post-stroke depression (PSD) is common and disabling, yet mechanism-based, multi-target therapies that jointly curb neuroinflammation and support cell survival are…

Date: 2026-07-02

Headache service quality in Egypt: current status, identified gaps, and strategic directions

Abstract: Headache disorders are a leading cause of disability worldwide, yet service delivery in low- and middle-income countries (LMICs) like Egypt remains understudied. This…

Date: 2026-07-02

Differences in postpartum depressive symptoms across survey waves among Chinese mothers and their association with structural resources: a repeated cross-sectional study based on CFPS data

Abstract: Using China Family Panel Studies data (CFPS; 2016, 2018, 2020, and 2022), this study examined between-sample differences in postpartum depressive symptoms across survey…

Date: 2026-07-02