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Prognostic value of the atherogenic index of plasma for early-stage diabetic kidney disease in type 2 diabetes: a retrospective cohort study using supervised machine learning

Abstract: Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease (ESRD). Its insidious onset means that once it progresses to the stage of heavy proteinuria…

Date: 2026-06-30

Vitamin K status has no influence on the effect of vitamin D supplementation on bone turnover and cardiovascular markers: a randomized controlled trial

Abstract: Vitamin K and D co-treatment may have additive effects on bone and cardiovascular health and is frequently used as an over-the-counter supplement. The primary aim of…

Date: 2026-06-30

Development and validation of a predictive model for diabetic kidney disease risk in patients with T2DM: a hospital data platform study

Abstract: This study used clinical data from patients with type 2 diabetes mellitus (T2DM) and applied least absolute shrinkage and selection operator (LASSO) regression to…

Date: 2026-06-30

Inflammation and nutrition-derived indicators for predicting amputation risk in patients with type 2 diabetic foot ulcers

Abstract: Inflammation and malnutrition affect the prognosis of diabetic foot ulcers (DFU). This study systematically evaluated the impact and predictive value of inflammation and…

Date: 2026-06-30

Systemic skewing of peripheral blood leukocyte composition in neurofibromatosis type 1

Abstract: The present study aimed to characterize neurofibromatosis type 1 (NF1)-associated alterations in peripheral white blood cell differentials, focusing on overall patterns…

Date: 2026-06-30

Awareness and attitudes of parents towards pediatric dentistry and children's oral health: a cross-sectional study

Abstract: Parents play a pivotal role in shaping children's oral health behaviors and practices. This study aimed to assess parental awareness and attitudes regarding children's…

Date: 2026-06-30

Serum beta-2 microglobulin as a diagnostic biomarker for pediatric Epstein–Barr virus infections: a retrospective study

Abstract: This study aims to evaluate serum beta-2 microglobulin (?2M) as a diagnostic biomarker for acute primary Epstein–Barr virus (EBV) infection in children, Additionally,…

Date: 2026-06-30

A retrospective cohort study on the impact of gonadotropin dose on embryo quality and pregnancy outcome: identification of optimal dose range

Abstract: The study investigates the impact of gonadotropin (Gn) dose on embryo quality and pregnancy outcome in patients receiving controlled ovarian stimulation (COS) with…

Date: 2026-06-30

Clinicopathological features of breast cancer in Ukrainian women with BRCA1 c.181T>G (p.Cys61Gly) variant: a case series

Abstract: BRCA1 c.181T>G (p.Cys61Gly) is a pathogenic founder genetic variant prevalent in Central and Eastern Europe. The data on its clinicopathological manifestations in…

Date: 2026-06-30

Stigma and quality of life in hospitalized schizophrenia patient-family caregiver dyads in Northern China: an actor-partner interdependence model analysis

Abstract: Schizophrenia is a chronic and relapsing mental disorder that is consistently associated with a severely diminished quality of life (QoL) for patients. Existing research…

Date: 2026-06-30