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Machine learning-driven identification and immunohistochemical validation of an integrated immune-inflammatory phenotype for disease-free survival stratification in breast cancer

Abstract: Recurrence risk in breast cancer remains heterogeneous, and conventional clinicopathological variables may not fully capture the contribution of immune-related factors.…

Date: 2026-06-18

Association between atherogenic index of plasma in early pregnancy and risk of preeclampsia: a multicenter cohort study

Abstract: This study aimed to investigate the relationship between atherogenic index of plasma (AIP) and preeclampsia (PE). This retrospective multicenter observational cohort…

Date: 2026-06-18

Establishment of a CT-based prediction model for endotracheal tube size in infants aged <1 year

Abstract: By quantifying airway parameters on computed tomography (CT) and incorporating clinical factors such as age and prematurity, this study developed an airway prediction…

Date: 2026-06-18

Declining age-adjusted mortality but persistent inequalities in chronic obstructive pulmonary disease in the United States, 1999–2024: a CDC WONDER analysis contextualized by GBD 2023

Abstract: Chronic obstructive pulmonary disease (COPD) remains a leading cause of premature mortality and disability worldwide. National averages in the United States often…

Date: 2026-06-18

Perioperative anesthetic management in pediatric heart transplantation: a single-center descriptive study involving 27 patients

Abstract: Orthotopic heart transplantation is the standard treatment for pediatric end-stage heart disease. Due to the wide age range and high physiological heterogeneity among…

Date: 2026-06-18

Development and validation of a risk nomogram for failed conversion from labor epidural analgesia to cesarean epidural anesthesia

Abstract: This study aimed to develop and validate a risk prediction nomogram for failed conversion from epidural labor analgesia to cesarean epidural anesthesia. Parturients…

Date: 2026-06-18

Conflict resolution strategies and their association with perceived stress among German medical students: a cross-sectional study

Abstract: Effective conflict management is essential in medical teams to maintain collaboration and ensure high-quality patient care. While teamwork, self-reflection, and conflict…

Date: 2026-06-18

Transforaminal versus interlaminar endoscopic approach for broad-based lumbar disc herniation under standardized postoperative mecobalamin therapy: a retrospective comparative study based on VAS and ODI

Abstract: This study aims to compare the clinical outcomes of the transforaminal approach (TFA) and interlaminar approach (ILA) for broad-based lumbar disc herniation (BLDH) under…

Date: 2026-06-18

Dynamic inflammatory markers as predictors of 90-day outcomes in spontaneous intracerebral hemorrhage

Abstract: To investigate the time-dependent characteristics of composite inflammatory biomarkers in patients with spontaneous intracerebral hemorrhage (ICH), and to evaluate the…

Date: 2026-06-18

Acupuncture is independently associated with improved recovery in Guillain–Barré syndrome: a prospective observational study

Abstract: Despite receiving standard intravenous immunoglobulin (IVIG) therapy, patients with Guillain–Barré syndrome (GBS) frequently suffer from delayed neurological recovery…

Date: 2026-06-18