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Association of neutrophil-to-prognostic nutritional index ratio with long-term mortality in acute myocardial infarction from Chinese and US cohorts

Abstract: Despite advancements in reperfusion strategies, patients with acute myocardial infarction (AMI) face significant risks of long-term mortality. Systemic inflammation and…

Date: 2026-06-18

OTUD7B exacerbates atherosclerosis by promoting RIPK1-dependent vascular smooth muscle cell necroptosis

Abstract: Atherosclerosis is a vascular disease characterized by lipid deposition, chronic inflammation, and cell death. Necroptosis, a form of programmed necrosis, plays a…

Date: 2026-06-18

Comparative efficacy and safety of etoposide plus PEG-rhG-CSF versus etoposide plus G-CSF for haematopoietic stem cell mobilisation in patients with multiple myeloma and lymphoma

Abstract: Efficient and safe mobilisation of haematopoietic stem cells is essential for successful autologous haematopoietic stem cell transplantation (ASCT). Although pegylated…

Date: 2026-06-17

Polymorphism analysis of estrogen receptor ? Gene RsaI and AluI in girls with idiopathic central precocious puberty: investigating the relationship and implications for early risk prediction

Abstract: To investigate the association between estrogen receptor ? ( ER? ) gene RsaI (rs1256049) and AluI (rs4986938) polymorphisms and the risk of idiopathic central precocious…

Date: 2026-06-17

Dulaglutide versus empagliflozin as add-on therapy to metformin and sulfonylurea in type 2 diabetes: a randomized pilot study with exploratory metabolomic and microbiome analyses

Abstract: In patients with type 2 diabetes mellitus (T2DM) inadequately controlled with metformin and sulfonylurea, evidence directly comparing glucagon-like peptide-1 receptor…

Date: 2026-06-17

Association between impaired peripheral thyroid hormone sensitivity and coronary heart disease in type 2 diabetes: the potential mediating role of albumin

Abstract: Type 2 diabetes mellitus (T2DM) is associated with a high risk of cardiovascular mortality, primarily from coronary heart disease (CHD). Thyroid hormone (TH) sensitivity…

Date: 2026-06-17

Is dry skin a clue to diabetic retinopathy? Clinical insights from the overall dry skin score

Abstract: Fluctuations in blood sugar and changes in water retention mechanisms in diabetes mellitus often cause dry skin in patients with diabetes. However, the impact of…

Date: 2026-06-17

MCM8 variants in two patients with primary ovarian insufficiency: clinical findings and in vitro defective DNA repair revealed by an MCM8 double-mutant construct

Abstract: Pediatric-onset primary ovarian insufficiency (POI) presents distinct clinical challenges, including delayed puberty or growth retardation. Previously, we reported a…

Date: 2026-06-17

Effectiveness of a structured diabetes self-management education program using high-definition video technology in type 1 diabetes: an interventional study

Abstract: One of the most common chronic disorders in children is type 1 diabetes (T1D). It requires regular evaluation, stringent glycemic control, and comprehensive education on…

Date: 2026-06-17

Multiplex PCR-based epidemiology of viral acute respiratory infections in hospitalized children: implications for antibiotic stewardship in Saudi Arabia

Abstract: Acute respiratory infections (ARIs) remain a leading cause of paediatric hospitalization worldwide. However, data describing viral epidemiology and management patterns…

Date: 2026-06-17