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Incidence, prevalence, and prognostic impact of sarcopenia on hepatic and cardiovascular outcomes in non-cirrhotic metabolic dysfunction–associated steatotic liver disease

Abstract: Sarcopenia is increasingly recognized as a clinically relevant comorbidity in metabolic dysfunction–associated steatotic liver disease (MASLD), yet its epidemiology and…

Date: 2026-06-11

Clinical features of type A aortic dissection initially presenting with neurological symptoms: a single-center case series

Abstract: Aortic dissection, a life-threatening condition, may present with neurological symptoms mimicking acute stroke, leading to delayed diagnosis and inappropriate…

Date: 2026-06-11

Longitudinal motor function and biomarker correlates in treated adult spinal muscular atrophy: a single-center cohort study

Abstract: Long-term clinical trajectories and accessible biomarkers in adult spinal muscular atrophy (SMA) remain insufficiently characterized under real-world treatment…

Date: 2026-06-11

Napkin-ring sign plaques are associated with clinical outcome in patients with acute ischemic stroke after endovascular therapy

Abstract: Few studies have investigated the association between the carotid artery napkin ring sign (NRS) and acute ischemic stroke (AIS). This study investigated whether the…

Date: 2026-06-11

Vitamin D supports activated CD4 + T-cell proliferation through enhanced glutaminolysis

Abstract: Vitamin D (VitD) is an important immunometabolic regulator of T cell function. Its active form, 1,25-dihydroxyvitamin D 3 , signals through the VitD receptor (VDR),…

Date: 2026-06-11

Antigen-scaffolds loaded with hyper-stable neoleukin-2/15 expand antigen-specific T cells with a favorable phenotype for adoptive cell therapy

Abstract: Adoptive cell therapy (ACT) has shown promising results in cancer treatment, however, achieving effective ex vivo expansion of potent, functionally active, and cytotoxic…

Date: 2026-06-11

Acetylcholine receptor antibody-positive myasthenia gravis and Kennedy’s disease overlap syndrome: a case report and literature review

Abstract: To investigate the clinical characteristics and electromyographic findings of a patient with acetylcholine receptor (AChR) antibody-positive myasthenia gravis (MG)…

Date: 2026-06-11

Effectiveness and safety of avelumab maintenance in patients aged ?75 years with advanced urothelial cancer: a sub-analysis of the meet-URO 25 (MALVA) study

Abstract: Avelumab maintenance therapy is an established therapeutic approach for patients with advanced urothelial carcinoma (UC) whose disease has not progressed after…

Date: 2026-06-11

Subsite-specific benefit of induction chemoimmunotherapy in HPV-negative oropharyngeal squamous cell carcinoma

Abstract: To evaluate whether the addition of immune checkpoint inhibitors (ICIs) to induction chemotherapy improves outcomes in HPV-negative oropharyngeal squamous cell carcinoma…

Date: 2026-06-11

Psychological predictors of functioning in patients with asthma

Abstract: Psychological characteristics significantly modify the impact of asthma on overall functioning. The emotional burden associated with the disease interacts with somatic…

Date: 2026-06-11