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Androgen profiling in adolescent girls with polycystic ovary syndrome

Abstract: To characterize global steroid hormone dysregulation and the androgen profile in adolescent girls with polycystic ovary syndrome (PCOS), and to explore adrenal versus…

Date: 2026-06-03

Predicting severe intraventricular hemorrhage in very preterm and/or very low birth weight infants: a nomogram approach

Abstract: Severe intraventricular hemorrhage (IVH) is a major brain injury in very preterm and/or very low birth weight infants. We developed a simple model to distinguish severe…

Date: 2026-06-03

Preliminary construction and validation of a prognostic prediction model for cervical cancer based on tumor mechanics-related genes

Abstract: Cervical cancer (CC) is the fourth most prevalent malignancy among women. The present study employed bioinformatics analyses to identify tumor mechanics-related genes…

Date: 2026-06-03

Comprehensive antiphospholipid antibody profiling and unsupervised immune phenotyping in fetal growth restriction

Abstract: Non-criteria antiphospholipid antibodies (aPLs) may be associated with adverse obstetric outcomes in patients who do not meet conventional antiphospholipid syndrome…

Date: 2026-06-03

Prediction model for postoperative delirium risk in elderly hypertensive patients: machine learning-based development and validation

Abstract: Postoperative delirium (POD) is a severe complication in elderly hypertensive patients, associated with poor long-term outcomes. Existing models often rely on…

Date: 2026-06-03

Neuronal exosomal miR-25-3p attenuates M1 microglial activation and neurotoxicity by targeting TLR4 to regulate the NF-?B signaling pathway

Abstract: Perioperative neurocognitive disorders (PND) are severe postoperative complications in the elderly, with neuroinflammation driven by pro-inflammatory M1 microglia being…

Date: 2026-06-03

Remimazolam is associated with superior cerebral and pulmonary protection over propofol in elderly thoracic surgery: a real-world study validated by propensity score matching

Abstract: Selecting the optimal anesthetic regimen to mitigate postoperative cognitive decline and pulmonary complications in elderly patients undergoing thoracic surgery remains…

Date: 2026-06-03

Reduced serum cortisol, IGF-1, GLP-1, and T3 levels in medication-free children and adolescents with obsessive–compulsive disorder: a case–control study

Abstract: Obsessive–compulsive disorder (OCD) frequently emerges during childhood and adolescence and has been associated with alterations in multiple neurobiological systems.…

Date: 2026-06-03

Quality assessment of dry eye educational videos on Xiaohongshu and differences by uploader type

Abstract: Xiaohongshu has become an important platform for the public to obtain eye health information, but the quality and uploader-related differences of dry eye educational…

Date: 2026-06-03

Vector outcomes after SMILE pro with the VISUMAX 800 for high versus moderate-to-low astigmatism: a contralateral eye comparison

Abstract: To evaluate vector outcomes and higher-order aberrations (HOAs) in eyes with high astigmatism (HA) and their contralateral eyes with moderate-to-low astigmatism (MLA)…

Date: 2026-06-03