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A study of sex and age related heterogeneity in thyroid-gonadal axis interactions in a multi-center cohort of individuals with normal thyroid function

Abstract: There is a complex physiological interaction between the HPT axis and the HPG axis. However, previous studies have primarily focused on individuals with thyroid…

Date: 2026-05-29

Obstructive sleep apnea risk and its association with diabetic foot ulcer in patients with type 2 diabetes

Abstract: Obstructive sleep apnea (OSA) is common in type 2 diabetes (T2D) and may contribute to its chronic complications. Whether STOP-Bang-defined OSA risk is associated with…

Date: 2026-05-29

Predictors of early response to GnRH and gonadotropin therapy in pediatric patients with suspected dual congenital hypogonadotropic hypogonadism: a retrospective single-center study

Abstract: Some patients with congenital hypogonadotropic hypogonadism (CHH) and suspected partial testicular impairment may show variable clinical responses to GnRH and…

Date: 2026-05-29

Visceral fat area and visceral-to-subcutaneous fat ratio are more strongly associated with residual cholesterol than conventional anthropometric indices in adults with type 2 diabetes

Abstract: Residual cholesterol (RC) is linked to cardiovascular risk, yet the optimal adiposity indices to capture this burden in type 2 diabetes (T2D) remain unclear. We compared…

Date: 2026-05-29

Correlation between cardiorespiratory fitness and body composition in individuals with different glucose metabolism statuses

Abstract: To investigate Cardiorespiratory Fitness indicators in populations with different glucose metabolism statuses and analyze their correlation with body composition. This…

Date: 2026-05-29

Patients with type 1 diabetes mellitus and recommended low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol and apolipoprotein B targets – a SwissDiab study

Abstract: Cardiovascular risk in type 1 diabetes mellitus (T1DM) is frequently underestimated in daily clinical practice. The aim was therefore to evaluate lipid management in…

Date: 2026-05-29

Integrative analysis links traditional Chinese medicine syndrome differentiation to multi-dimensional skin phenotypes and predicts therapeutic response in photographs

Abstract: Traditional Chinese medicine (TCM) syndrome differentiation guides personalized treatment; however, its biological basis remains objectively uncharacterized in…

Date: 2026-05-29

Plasmacytoid dendritic cells alleviate atopic dermatitis by suppressing Th2 inflammation via the IFN-?/IFNAR1 pathway

Abstract: Atopic dermatitis (AD) is a chronic immune-mediated inflammatory skin disease characterized by persistent pruritus and eczematous lesions. Its core pathophysiology…

Date: 2026-05-29

Prospective longitudinal study of psychological sequelae, self-perception of body image, and quality of life in severe cutaneous adverse drug reactions: a case-control study

Abstract: Severe cutaneous adverse drug reactions (SCARs) are associated with mental health sequelae and reduced quality of life. However, existing research is limited by small…

Date: 2026-05-29

Integrated systems toxicology identifies TCDD-responsive targets linked to immune dysregulation and treatment response in psoriasis

Abstract: Psoriasis is a chronic immune-mediated inflammatory skin disease driven by dysregulation of the IL-23/IL-17 axis and influenced by genetic and environmental factors. The…

Date: 2026-05-29