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Health-related quality of life after autologous stem cell transplantation for multiple myeloma or lymphoma impacts professional activity- an analysis from two German tertiary care centers

Abstract: Autologous stem cell transplantation (ASCT) for the treatment of multiple myeloma and lymphoma patients has been reported to improve relapse-free (RFS) and overall…

Date: 2026-05-28

Burden of disease attributable to tobacco, high alcohol use, and drug use from 1990 to 2021

Abstract: Substance use, including tobacco, high alcohol use, and drug use, has negative consequences on the health, economy, productivity, and social aspects of communities.…

Date: 2026-05-28

Secular trends in HbA1c levels among children and adolescents with type 1 diabetes

Abstract: The management of type 1 diabetes (T1D) has significantly improved over the past two decades in parallel with advancements such as medical nutrition therapy, long-acting…

Date: 2026-05-28

Prognostic nutritional index at discharge as a practical bedside tool for long-term all-cause mortality risk in pneumonia-induced sepsis survivors

Abstract: Existing research has predominantly focused on short-term outcomes of sepsis during intensive care unit (ICU) admission, with limited evidence on long-term all-cause…

Date: 2026-05-28

Cardiac and aerobic response to growth hormone therapy in children with short stature: a prospective study using VO 2 max and speckle tracking echocardiography

Abstract: Recombinant human growth hormone (r-hGH) enhances somatic growth and body composition, yet its short-term effects on aerobic capacity and myocardial function remain…

Date: 2026-05-28

Familial glucocorticoid deficiency due to a novel TXNRD2 variant: expanding the spectrum of a rare genetic cause

Abstract: Familial glucocorticoid deficiency (FGD) is a rare autosomal recessive disorder characterized by isolated cortisol deficiency and elevated adrenocorticotropic hormone…

Date: 2026-05-28

Isoflurane for difficult sedation in critically ill children: a retrospective analysis in a mixed pediatric intensive care population

Abstract: When standard intravenous regimens fail, children in the pediatric intensive care unit often face escalating sedative polypharmacy with potential harm; we therefore…

Date: 2026-05-28

An evaluation of factors associated with hypertension in children and adolescents with obesity

Abstract: Childhood hypertension and obesity are among the most prevalent health conditions worldwide, with obesity increasing the risk of hypertension in children. However, there…

Date: 2026-05-28

TP53 deficiency induces a low-adhesion transcriptomic signature correlating with accelerated CAR-T cell exhaustion in B-ALL

Abstract: Chimeric antigen receptor T-cell (CAR-T) therapy is a potent treatment for relapsed/refractory B-cell acute lymphoblastic leukemia (R/R B-ALL). However, patients…

Date: 2026-05-28

Insights into epidemiological and clinical burden of bronchiolitis among hospitalized children: a call for preventive interventions

Abstract: Bronchiolitis is a leading cause of hospitalization in infants under 2 years, with seasonal surges that strain healthcare systems. Despite its prevalence, management…

Date: 2026-05-28