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Cutaneous adverse events with antibody-drug conjugates: a FAERS-based pharmacovigilance study

Abstract: Antibody-drug conjugates (ADCs) have revolutionized oncology by integrating the target specificity of monoclonal antibodies with the potency of cytotoxic payloads.…

Date: 2026-05-25

Progression-directed ablative radiotherapy improves event-free survival in oligoprogressive NSCLC

Abstract: To assess the efficacy of progression-directed radiation therapy (PDRT) in patients with oligoprogressive non-small cell lung cancer (NSCLC), with particular focus on…

Date: 2026-05-25

Mechanistic and functional characterization of NETs/IL-17 as a therapeutic target in EMT and brain metastasis of lung adenocarcinoma

Abstract: Lung adenocarcinoma (LUAD) was known to have a propensity for brain metastasis. Neutrophil extracellular traps (NETs) played a role in facilitating tumor metastasis.…

Date: 2026-05-25

Immunotherapy plus induction chemotherapy followed by radiotherapy alone or one cycle of concurrent chemotherapy with cisplatin vs induction chemotherapy followed by two cycles of concurrent chemotherapy with cisplatin in locoregionally advanced nasopharyngeal carcinoma

Abstract: To compare the efficacy and safety of immunotherapy combined with induction chemotherapy followed by radiotherapy alone or one cycle of concurrent chemoradiotherapy with…

Date: 2026-05-25

Early osseointegration of two in-house 3D-printed porous titanium implant designs: an in vivo sheep study

Abstract: Early osseointegration is critical for long-term implant stability, and in-house 3D–printed porous surfaces may enhance bone integration by promoting cellular migration…

Date: 2026-05-25

Analysis of factors associated with cognitive impairment in elderly patients hospitalized with chronic heart failure

Abstract: This study systematically investigates the prevalence of cognitive impairment (CI) and its associated factors among older inpatients with chronic heart failure (CHF),…

Date: 2026-05-25

Role of psychological resilience and psychological distress in linking fear of disease progression to quality of life in chronic heart failure: a cross-sectional serial mediation analysis

Abstract: To examine whether psychological resilience and psychological distress serially mediate the association between fear of disease progression and quality of life (QoL) in…

Date: 2026-05-25

Analysis of pathogen distribution and association with lipid levels in patients with diabetic foot

Abstract: Diabetic foot infection (DFI) is a severe complication of diabetes, and dyslipidemia is common in affected patients. However, the relationship between lipid profiles,…

Date: 2026-05-22

Joint trajectories of objective physical function and cognition and risk of incident dementia: a population-based cohort study

Abstract: This study aimed to identify joint longitudinal trajectories of physio-cognitive aging, determine the temporal precedence between physical and cognitive decline, and…

Date: 2026-05-22

Modulation of chemokine secretion and oxidative stress in vitro in thyroid cells after exposure to thiocyanate, nitrate, or perchlorate

Abstract: Perchlorate, nitrate, and thiocyanate are thyroid disruptors. Emerging evidence suggests they may exert further effects independent of iodide uptake inhibition,…

Date: 2026-05-22