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The B7-H3/CD3 immune phenotype identifies prognostic subgroups in neuroblastoma

Abstract: B7-H3 is an immune checkpoint molecule implicated in tumor immune evasion and adverse prognosis in multiple malignancies. This study aimed to characterize the…

Date: 2026-05-18

Factors associated with anemia among adolescent girls in Western India: insights from a multi-centric cross-sectional study

Abstract: Anemia remains a persistent public health challenge among adolescent girls in India, with states like Gujarat continuing to report a high burden despite ongoing national…

Date: 2026-05-18

Association between the composite CRP–TyG index and incident malignancy risk in hospitalized patients with diabetes: a retrospective cohort study with nonlinear effect analysis

Abstract: Diabetes mellitus is increasingly recognized as a risk factor for malignancy, partly through chronic low-grade inflammation and insulin resistance. The composite…

Date: 2026-05-18

Optimization of nursing strategies for semaglutide treatment in overweight type 2 diabetes based on gene polymorphism

Abstract: To evaluate the impact of a gene polymorphism-based individualized nursing strategy on the efficacy of semaglutide in overweight type 2 diabetes (T2DM) patients and to…

Date: 2026-05-18

Association between Staphylococcus aureus colonization and clinical improvement in pediatric atopic dermatitis treated with dupilumab: a pilot study

Abstract: Moderate-to-severe atopic dermatitis (AD) in children is characterized by impaired skin barrier function, type 2 inflammation, and frequent Staphylococcus aureus…

Date: 2026-05-18

Microcrystalline tyrosine as a novel depot-forming agent in venom immunotherapy: a pre-clinical evaluation in bee-venom allergic mice

Abstract: Venom immunotherapy (VIT) with aqueous venom extracts is a standard treatment for severe insect venom allergies. In other fields of allergen immunotherapy (AIT), depot…

Date: 2026-05-18

A prediction nomogram for faltering catch-up growth in full-term small-for-gestational-age infants: a retrospective cohort study

Abstract: Catch-up growth (CUG) before two years of age in small-for-gestational-age (SGA) infants is a key predictor of adult short stature. We aimed to establish and temporally…

Date: 2026-05-18

Aberrant IL-21/STAT3 signaling disrupts regulatory T cell function and CD4 + T cell homeostasis in children with type 1 diabetes

Abstract: Type 1 diabetes (T1D) is an autoimmune disease characterized by profound dysregulation of CD4 + T cell subsets, particularly impaired regulatory T cell (Treg) function…

Date: 2026-05-18

Comparison of the therapeutic performance of macrolide antibiotics on macrolide-resistant or macrolide-susceptible Mycoplasma pneumoniae pneumonia children

Abstract: This research aims to investigate the performance of macrolide antibiotics for the treatment of Mycoplasma pneumoniae pneumonia (MPP) in children with or without…

Date: 2026-05-18

Clinical utility of an evolving cholestasis gene panel in 10,000 children and adults

Abstract: Cholestasis has diverse causes, with genetic factors playing a key role. Diagnosis is challenging due to varied presentations and overlapping genetic conditions.…

Date: 2026-05-18