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Characteristics of patients with cryptogenic stroke and atrial fibrillation detected using insertable cardiac monitoring in the chronic phase: a subanalysis of the LOOK study

Abstract: Occult atrial fibrillation (AF) is a major underlying cause of cryptogenic stroke (CS) and is frequently identified only after hospital discharge. However, the…

Date: 2026-05-15

Early neural shift detection using functional magnetic resonance imaging: a pilot study with Parkinson’s disease patients undergoing istradefylline and hybrid assistive limb interventions

Abstract: Parkinson’s disease (PD) presents with not only motor symptoms but also non-motor features, including cognitive impairment. Although conventional assessments usually…

Date: 2026-05-15

The endocrine pathway during whole body vibration modulates the immune system and the osteogenesis in postmenopausal women with osteoporosis

Abstract: Osteoimmunology is an interdisciplinary field that investigates the interaction between the immune and skeletal systems in the context of immune regulation of bone…

Date: 2026-05-15

Gut microbiome functional pathways outperform taxonomic profiles in predicting immune checkpoint inhibitor response in non-small cell lung cancer: an interpretable machine learning approach with SHAP

Abstract: Lung cancer remains the leading cause of cancer mortality worldwide, with non-small cell lung cancer (NSCLC) accounting for the majority of cases. Although immune…

Date: 2026-05-15

Phase I/II, open-label, multicenter study of durvalumab in combination with tremelimumab in pediatric patients with advanced solid tumors

Abstract: We conducted a phase I/II study to evaluate durvalumab (D; anti-PD-L1) in combination with tremelimumab (T; anti–cytotoxic T-lymphocyte antigen 4) in pediatric patients…

Date: 2026-05-15

Neoadjuvant camrelizumab in combination with chemotherapy followed by sequential radical surgery for locally advanced esophageal squamous cell carcinoma: postoperative pathological remission characteristics and influencing factors

Abstract: Neoadjuvant camrelizumab combined with chemotherapy has shown favorable efficacy and safety profiles in the treatment of locally advanced esophageal squamous cell…

Date: 2026-05-15

Prognostic significance of atrial functional mitral regurgitation in patients with HFpEF and end-stage renal disease

Abstract: Atrial functional mitral regurgitation (AFMR) is common in patients with heart failure with preserved ejection fraction (HFpEF) and end-stage renal disease (ESRD)…

Date: 2026-05-15

Integrative multivariate genomic analysis reveals shared genetic determinants and druggable targets for vascular calcification

Abstract: Vascular calcification (VC), characterized by calcium deposition in arterial walls, is a major risk factor for cardiovascular morbidity and mortality. While genome-wide…

Date: 2026-05-15

Influence of nursing cardiac rehabilitation on cardiac function and quality of life in patients with coronary heart disease after percutaneous coronary intervention

Abstract: With the widespread application of Percutaneous coronary intervention (PCI) is widely used to treat coronary heart disease (CHD). Although it can effectively open…

Date: 2026-05-15

Systemic immune-inflammation Index and blood pressure control are independent and interactive predictors of atrial fibrillation recurrence after ablation

Abstract: Atrial fibrillation (AF) recurrence remains a major limitation after radiofrequency catheter ablation (RFCA), especially in patients with hypertension. Systemic…

Date: 2026-05-15