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Joint association of estimated skeletal muscle mass index and prognostic nutritional index with all-cause mortality in individuals with non-metastatic nasopharyngeal cancer

Abstract: The prognostic interplay between skeletal muscle mass and nutritional/immune status in non-metastatic nasopharyngeal carcinoma (NPC) is unclear. This study investigates…

Date: 2026-05-14

Integrating sarcopenia into ICU-acquired weakness risk stratification: a machine learning–based prediction model for critical care

Abstract: Sarcopenia is closely associated with weakness in elderly and various chronic disease populations. However, its specific role as a predisposing factor for ICU-acquired…

Date: 2026-05-14

Intermittent fasting alleviates irradiation-induced neuronal mitochondrial damage in mice

Abstract: Radiation-induced brain injury (RIBI) is a common side effect of cranial radiotherapy. Intermittent fasting (IF) decreases the risk of Brain aging disease by affecting…

Date: 2026-05-14

Thyroid markers in early to mid-pregnancy and risk of gestational diabetes: a longitudinal retrospective cohort study

Abstract: Thyroid markers have been associated with an increased risk of gestational diabetes mellitus (GDM), but existing evidence remains inconsistent. The purpose of this study…

Date: 2026-05-14

Cancer patients’ insights and experience of palliative and supportive care in the UAE: a qualitative study

Abstract: The increasing prevalence of advanced cancer cases requiring palliative care highlights the growing need for palliative care as an essential component of comprehensive…

Date: 2026-05-14

BMI-specific nonlinear associations and threshold effects of the atherogenic index of plasma on incident prediabetes: insights from 100473 Chinese adults

Abstract: Emerging evidence suggests that the atherogenic index of plasma (AIP), a simple marker of lipid-related metabolic risk, may relate to dysglycemia in a nonlinear fashion.…

Date: 2026-05-14

Effect of stress-induced hyperglycaemia on clinical outcome in paitients with acute ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention

Abstract: Stress hyperglycemia (SHG) is a transient glycemic disturbance induced by acute stress, and its independent prognostic value in patients with acute ST-segment elevation…

Date: 2026-05-14

Uromodulin as a genetically anchored biomarker stratifies time to valve intervention in aortic regurgitation

Abstract: Aortic regurgitation (AR) frequently remains asymptomatic for prolonged periods, with guideline recommendations for intervention largely guided by imaging-based…

Date: 2026-05-14

Data-driven computational modeling of CAR-T cell function

Abstract: The complex dynamics of chimeric antigen receptor T-cell (CAR-T cell) cytotoxicity and proliferation are potential factors that influence the clinical response to CAR-T…

Date: 2026-05-13

Integrated RNA-seq and sQTL analysis reveal immune and splicing regulatory features underlying relapse and remission after treatment of Graves’ disease

Abstract: Graves' disease (GD) is a classical autoimmune disorder caused by interactions between genetic susceptibility and immune dysregulation. However, the transcriptomic…

Date: 2026-05-13