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Elevated lactate dehydrogenase-to-albumin ratio: a novel and independent predictor of ventricular aneurysm in STEMI patients

Abstract: Left ventricular aneurysm (LVA) is a major mechanical complication following acute ST-segment elevation myocardial infarction (STEMI). This study aimed to evaluate the…

Date: 2026-05-13

CHA 2 DS 2 -VA score for predicting ventricular arrhythmias and mortality in ICD patients with ischemic heart disease and dilated cardiomyopathy: results from a prospective cohort

Abstract: The revised CHA 2 DS 2 -VA score facilitates stroke risk assessment in patients with atrial fibrillation. This study investigates the value of the CHA 2 DS 2 -VA for…

Date: 2026-05-13

Interpretable machine learning to predict NOAF in ICU patients with CKD: validation in US and Chinese cohorts

Abstract: Critically ill patients with chronic kidney disease (CKD) are at high risk for New-Onset Atrial Fibrillation (NOAF), which significantly increases their risk of adverse…

Date: 2026-05-13

Adherence to the EAT-Lancet diet and the risk of heart failure in individuals with cardiovascular-kidney-metabolic syndrome stages 0–3: A prospective cohort study

Abstract: In 2019, the EAT-Lancet Commission on Healthy Diets from Sustainable Food Systems proposed the EAT-Lancet planetary health diet as a universal reference dietary pattern…

Date: 2026-05-13

Multicenter development and validation of machine-learning risk models to predict procedural complete revascularization and in-hospital heart failure in STEMI patients treated with primary PCI

Abstract: In-hospital heart failure (HF) remains common after primary percutaneous coronary intervention (PPCI) for ST-segment elevation myocardial infarction (STEMI) and is…

Date: 2026-05-13

A novel marker for predicting malignancy in patients with thyroid nodules diagnosed as AUS on initial cytology: thyroid hormone sensitivity

Abstract: This study aimed to evaluate the predictive value of thyroid hormone sensitivity indices and hematological inflammatory markers, in addition to ultrasonographic…

Date: 2026-05-12

QDPR rs3733570 polymorphism is associated with type 2 diabetes and diabetic kidney disease accompanied by hyperlipidemia in the Chinese Han population

Abstract: Genetic factors play important roles in the development of type 2 diabetes mellitus and its complications. Diabetic kidney disease, a common microangiopathic…

Date: 2026-05-12

Identification and preliminary clinical validation of type 2 diabetes signature genes through machine learning analysis of scRNA-seq data

Abstract: Type 2 diabetes (T2DM) is a highly prevalent metabolic disorder with substantial molecular heterogeneity, and traditional bulk transcriptomic approaches often fail to…

Date: 2026-05-12

Diagnosis, treatment, and biosafety protection of imported highly pathogenic cutaneous fungal infection: a case-based study of cutaneous coccidioidomycosis

Abstract: Coccidioidomycosis is a significant fungal disease primarily endemic to the southern United States, northern Mexico, and South America. Coccidioidomycosis is non-endemic…

Date: 2026-05-12

A decade-long real-world cohort (2016–2025): development of an individualized risk-stratification nomogram and evaluation of clinical utility for recurrent respiratory tract infections in children

Abstract: Recurrent respiratory tract infections (RRTIs) are common in children and are associated with substantial healthcare costs and reduced quality of life. A practical tool…

Date: 2026-05-12