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Machine learning methods to predict leprosy misdiagnosis in Yunnan Province, People's Republic of China

Abstract: Leprosy is a chronic infectious disease caused by Mycobacterium leprae that is often misdiagnosed. This study aimed to identify factors associated with leprosy…

Date: 2026-05-08

Dissecting age-specific genetic architecture of vitiligo through integrative Post-GWAS analysis

Abstract: Vitiligo is a chronic acquired depigmentation disorder with a global prevalence of 0.5-2%. Early-onset (EO) and late-onset (LO) subtypes exhibit marked differences in…

Date: 2026-05-08

Diagnostic performance of wearable acoustic–electrocardiographic indices for screening secundum atrial septal defect in children

Abstract: To evaluate the diagnostic performance of acoustic–electrocardiographic indices derived from a wearable phonocardiogram–electrocardiogram (ECG) sensor for screening…

Date: 2026-05-08

Glycocalyx biomarkers as early predictors of endotheliopathy in pediatric and young adult hematopoietic stem cell transplantation patients

Abstract: Discovery of biomarkers predictive of endotheliopathy after hematopoietic stem cell transplant (HSCT) has the potential to more rapidly identify vulnerable patients,…

Date: 2026-05-08

LMS-based continuous reference values for the myokine musclin in serum in children and adults

Abstract: Musclin is a myokine which is linked to muscle activity and systemic metabolic regulation. Age-specific reference values for serum musclin are lacking in both the…

Date: 2026-05-08

Construction of a nomogram combining CT and serum markers for predicting macrolide resistance gene mutation status in pediatric Mycoplasma pneumoniae pneumonia

Abstract: To develop and validate a nomogram integrating chest computed tomography (CT) features and serum biomarkers for predicting the mutation status of macrolide resistance…

Date: 2026-05-08

Broadly neutralizing antibody-secreting CAR-T cells elicit Fc-mediated effector functions in vitro and suppress HIV in humanized mice

Abstract: Despite significant advances in antiretroviral therapy (ART), human immunodeficiency virus (HIV) persists in long-lived viral reservoirs, requiring lifelong treatment…

Date: 2026-05-08

Uterine-Sparing vNOTES vs. laparoscopic lateral suspension for pelvic organ prolapse repair: a prospective comparative study of feasibility and early outcomes

Abstract: Vaginal natural orifice transluminal endoscopic surgery (vNOTES) represents a minimally invasive uterus-preserving technique for apical prolapse repair. Comparative data…

Date: 2026-05-08

Particulate matter exposure induces maternal scalp hair loss after birth in C57/B6 mouse via alteration of inflammatory and apoptotic pathways

Abstract: PM 2.5 exposure is associated with a variety of health effects, including effects on the reproductive and skin. However, the relationship between PM2.5 exposure and…

Date: 2026-05-08

Comparative outcomes of robotic single-port vNOTES versus robotic-Xi assisted single-incision transumbilical surgery for hysterectomy

Abstract: This study was to evaluate the safety and feasibility of robotic single-port transvaginal natural orifice transluminal endoscopic surgery (RSP-vNOTES) compared with…

Date: 2026-05-08