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Subtype-specific effects of clonal hematopoiesis on cerebrovascular and cardiometabolic disease risk

Abstract: Cerebrovascular and related cardiometabolic diseases frequently cluster in aging populations characterized by metabolic dysfunction and chronic inflammation. Clonal…

Date: 2026-04-28

A study on the relationship between mMRC dyspnea scale and both risk stratification and poor prognosis in patients with acute pulmonary embolism

Abstract: This study aimed to investigate the value of the modified Medical Research Council (mMRC) dyspnea scale in risk stratification and outcome assessment for patients with…

Date: 2026-04-28

Development and validation of interpretable machine learning models for predicting stroke in NVAF patients with CHA 2 DS 2 -VA scores ?1

Abstract: Non-valvular atrial fibrillation (NVAF) patients with CHA?DS?-VA ?1 face uncertainty in stroke risk assessment, particularly in Asian populations. Machine-learning (ML)…

Date: 2026-04-28

Infection-associated sTNFR1 elevation predicts post-transplant thrombotic microangiopathy in severe aplastic anemia

Abstract: Transplant-associated thrombotic microangiopathy (TA-TMA) is a severe and potentially fatal complication following allogeneic hematopoietic stem cell transplantation…

Date: 2026-04-27

Determinants of survival in patients treated with CPX-351 for acute myeloid leukemia

Abstract: CPX-351 for the treatment of acute myeloid leukemia (AML) has demonstrated better efficacy compared with standard chemotherapy regimens, with an excellent safety…

Date: 2026-04-27

Comparative predictive value of the cholesterol-high-density lipoprotein-glucose index versus the triglyceride-glucose index for gestational dysglycemia: a two-cohort study

Abstract: Early risk stratification for gestational dysglycemia is important for improving maternal and neonatal outcomes. Derived from fasting triglycerides and glucose, the…

Date: 2026-04-27

Clinical predictors of tocilizumab response in moderate-to-severe thyroid eye disease: a large single-center retrospective cohort study

Abstract: Tocilizumab (TCZ), an interleukin-6 receptor antagonist, is recommended as a second-line therapy for thyroid eye disease (TED), yet the clinical determinants of…

Date: 2026-04-27

Not all adenomyosis is equal: impact of direct adenomyosis features on live birth after ART cycles in a prospective cohort study

Abstract: To evaluate whether the presence and type of ultrasound markers of adenomyosis, as defined by MUSA criteria, predict IVF/ICSI outcomes, specifically live birth and…

Date: 2026-04-27

Sleep duration, depressive symptoms, and postoperative delirium: a mediation analysis

Abstract: The mechanism linking postoperative sleep duration to postoperative delirium (POD) remains unclear. This study examined the potential indirect pathway involving…

Date: 2026-04-27

Association between estimated pulse wave velocity and impaired fasting glucose: a multicenter retrospective cohort study in China

Abstract: Prediabetes, primarily impaired fasting glucose (IFG), represents a critical window for preventing diabetes and its vascular sequelae. Estimated pulse wave velocity…

Date: 2026-04-27