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Peripheral immune and kynurenine profiles are associated with cognitive change during early treatment of first-episode schizophrenia

Abstract: To delineate the longitudinal relationships among peripheral inflammation, kynurenine pathway (KP) dysregulation, immune-cell redistribution, and cognitive performance…

Date: 2026-03-25

Analysis of the gender-specific risk factors of social anxiety among left-behind middle school students in Deyang

Abstract: Left-behind children in China often experience mental health challenges, including social anxiety (SA). Gender-related factors may play a key role in the development of…

Date: 2026-03-25

Association of table salt use with sleep patterns and depressive symptoms: population-based analysis with external clinical replication

Abstract: Dietary habits are modifiable factors related to sleep health, yet the association between discretionary table-salt use and sleep patterns—and the potential role of…

Date: 2026-03-25

Prevalence and influencing factors associated with the risk of malnutrition among long-term inpatients with schizophrenia in China

Abstract: Schizophrenia is a chronic, severe, and disabling neuropsychiatric disorder. In recent years, growing evidence suggests that nutrition may be strongly involved in the…

Date: 2026-03-25

Epigenetic dichotomy in florid vs. gliotic proliferative diabetic retinopathy: hypomethylation of EGLN1 and MMP9 drives divergent pathogenic pathways in angiogenesis and fibrosis

Abstract: This exploratory, hypothesis-generating study aimed to investigate methylation differences in 16 angiogenesis- and fibrosis-related genes across diabetic retinopathy…

Date: 2026-03-25

The role of elastic intramedullary nailing with or without Kirschner wire fixation in pediatric radial neck fractures: a retrospective cohort study

Abstract: To compare the clinical and functional outcomes of elastic intramedullary nailing (EN) alone vs. elastic intramedullary nailing combined with Kirschner wire fixation…

Date: 2026-03-25

A practice-embedded, PDSA-guided implementation study of continuing professional development for stoma care in a resource-constrained setting

Abstract: Continuing professional development (CPD) in resource-constrained clinical settings is frequently challenged by time pressures, staffing constraints, and limited…

Date: 2026-03-25

Efficacy of endoscopic retrograde appendicitis therapy in children with suppurative vs. simple appendicitis: a retrospective cohort study

Abstract: To evaluate the efficacy of endoscopic retrograde appendicitis therapy (ERAT) in the treatment of pediatric suppurative appendicitis. In this retrospective cohort study,…

Date: 2026-03-25

Helicobacter pylori infection is independently associated with triglyceride levels: a propensity score–matched cross-sectional study

Abstract: Helicobacter pylori ( H. pylori ) infects more than 50% of the global population and is associated with a variety of upper gastrointestinal diseases. In recent years,…

Date: 2026-03-25

Endoscopic direct-vision therapy for acute uncomplicated appendicitis: a retrospective study

Abstract: Acute uncomplicated appendicitis is common. Laparoscopic appendectomy (LA) is definitive but invasive, while endoscopic retrograde appendicitis therapy (ERAT) carries…

Date: 2026-03-25