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The surgical efficiency of Kirschner wire sleeve-assisted removal of elastic intramedullary nails: a comparative study

Abstract: Elastic intramedullary nails (ESIN) are widely used for pediatric fractures; however, their removal poses technical challenges. Currently, there are limited reports on…

Date: 2026-01-29

Longitudinal trajectory of gross motor skills in school-aged children with Rett syndrome

Abstract: In children with Rett syndrome, this study aimed to (1) describe gross motor skill trajectories; and (2) analyse the influences of genetic variant and comorbidities.…

Date: 2026-01-29

Impact of maternal visceral leishmaniasis on sex-specific immune responses and pathogenesis in offspring following homologous infections

Abstract: Leishmania donovani (Ld), the etiological agent of visceral leishmaniasis, has recently been implicated in vertical transmission, raising concerns about the potential…

Date: 2026-01-29

The importance of staying within range: associations between tacrolimus intrapatient variability and kidney transplant outcomes

Abstract: Kidney transplantation remains the treatment of choice for end-stage kidney disease. Maintaining immunosuppression within the appropriate therapeutic range is essential…

Date: 2026-01-29

Bcl-2 inhibitor resistance in diffuse large b-cell lymphoma: establishing a prognostic signature and targeting alpha protein kinase 1

Abstract: Drug resistance in diffuse large B-cell lymphoma (DLBCL) contributes to poor prognosis in 30–40% of newly diagnosed patients in the era of first-line rituximab combined…

Date: 2026-01-28

Gut microbiota interactions with the immunomodulatory role of 25-hydroxyvitamin D in children with infectious mononucleosis

Abstract: Infectious mononucleosis (IM) is a childhood infectious disease caused by the Epstein–Barr virus (EBV). Its pathogenesis is associated with immune and gut microbiota…

Date: 2026-01-28

Safety and feasibility assessment of implantable chest wall venous access port for patients with acute leukemia

Abstract: Totally implantable venous access ports (TIVAPs) are widely used in chemotherapy for solid malignant tumors. However, there are currently few data on the application of…

Date: 2026-01-28

The triglyceride-glucose index in relation to psychotic symptoms in adolescents with major depressive disorder

Abstract: It is increasingly recognized that insulin resistance (IR) is associated with major depressive disorder(MDD) and a spectrum of psychotic symptoms. However, a paucity of…

Date: 2026-01-28

Total flavonoids from Abelmoschus manihot (L.) improve diabetes nephropathy by regulating the gut–kidney axis

Abstract: A recent clinical study demonstrated that Huangkui capsule (with its bioactive constituents being total flavones extracted from Abelmoschus manihot (L.), TFA) combined…

Date: 2026-01-28

Association between metabolic dysfunction-associated fatty liver disease and cardiovascular autonomic neuropathy in type 2 diabetes

Abstract: This cross-sectional study aimed to elucidate the relationship between metabolic dysfunction-associated fatty liver disease (MAFLD) and diabetic cardiovascular autonomic…

Date: 2026-01-28