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Promiscuous class II-binding SARS-CoV-2-nuc derived vaccine-peptide induced extensive conventional, innate and unconventional T cell responses

Abstract: We describe the T-cell response of two healthy SARS-CoV-2-unexposed volunteers to a SARS-CoV-2 nucleoprotein-derived vaccine peptide predicted to promiscuously bind…

Date: 2025-11-11

Global burden, trends, and inequalities in cancer and subtypes attributable to high BMI among older adults, 1990–2021: a secondary analysis of the global burden of disease study 2021

Abstract: High body mass index (BMI) is a significant modifiable risk factor for cancer, yet its global burden in older adults (aged ?60 years) remains incompletely understood.…

Date: 2025-11-11

Constrains for seeking perimenopausal healthcare services among women aged 40–60 years in Guangzhou, China: a cross-sectional study

Abstract: In China, the vast majority of perimenopausal healthcare (PMH) services are performed in a diversity of outpatient clinics, such that women may encounter more obstacles…

Date: 2025-11-11

OCTA-based evaluation of the correlation between macular retinal and choroidal structural characteristics and refractive status in patients with retinopathy of prematurity

Abstract: To investigate the correlation between macular retinal and choroidal structural characteristics and refractive status in preschool-aged children with retinopathy of…

Date: 2025-11-11

The effect of enhanced recovery after surgery on the risk factors of venous thromboembolism for patients with gynecologic malignancies

Abstract: This study aims to evaluate the efficacy of enhanced recovery after surgery (ERAS) in mitigating the risk of venous thrombosis in patients undergoing surgery for…

Date: 2025-11-10

The impact of hormonal fluctuations and the efficacy of targeted hormonal interventions in improving macular hole outcomes

Abstract: Macular hole formation is influenced by vitreoretinal dynamics, with hormonal status playing a critical role in retinal stability. Reduced estrogen and testosterone…

Date: 2025-11-10

Autologous platelet-rich gel versus vitamin B12 for the treatment of grade III-IV acute radiation dermatitis in malignant tumor patients undergoing radiotherapy: an open-label randomized controlled clinical trial

Abstract: Acute radiation-induced dermatitis (ARD) remains the most prevalent adverse event associated with radiotherapy;however, effective management options remain limited.This…

Date: 2025-11-07

The associations of maternal serum ferritin levels with hypertensive disorders of pregnancy: a longitudinal cohort study

Abstract: The longitudinal fluctuations in maternal serum ferritin (SF) levels during gestation, acting as indirect indicators of iron supplementation, have not been thoroughly…

Date: 2025-11-07

Childhood lymphadenopathy: ultrasonographic predictors of malignancy in a retrospective cohort of 500 patients

Abstract: Pediatric lymphadenopathy is common and usually benign, yet selecting children who need biopsy remains challenging. We evaluated clinical and ultrasonographic (US)…

Date: 2025-11-06

Diagnostic utility of reticulocyte hemoglobin for iron-restricted anemia in patients with end-stage kidney disease on hemodialysis

Abstract: Chronic kidney disease (CKD) is a serious, long-term illness that damages kidneys and lowers glomerular filtration rate. CKD often causes anemia. Iron deficiency (ID) is…

Date: 2025-11-06