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Association between sunlight exposure and risk of rheumatic diseases: a prospective cohort study in the UK

Abstract: To investigate the relationships between sunlight exposure and the risk of three major rheumatic diseases (systemic lupus erythematosus [SLE], rheumatoid arthritis [RA],…

Date: 2026-09-14

Pre-radiotherapy cachexia is associated with treatment discontinuation in patients with head and neck squamous cell carcinoma receiving definitive radiotherapy

Abstract: This study aimed to evaluate the association between pre-radiotherapy cachexia and treatment discontinuation, as well as other treatment-related outcomes, in patients…

Date: 2026-09-14

Clinical characteristics of immune-related adverse events after immune checkpoint inhibitor therapy with or without chemotherapy in patients with antinuclear antibody-positive malignancies

Abstract: Antinuclear antibodies (ANA) are detected in cancer patients before ICI therapy, but their association with immune-related adverse events (irAEs) and outcomes is…

Date: 2026-09-14

Predictors of osteoporosis self-efficacy among young and middle-aged female nurses based on self-efficacy theory and the health belief model: evidence from a tertiary hospital in Eastern China

Abstract: Young and middle-aged female nurses face an elevated risk of osteoporosis due to occupational demands and progressive physiological bone loss. However, most existing…

Date: 2026-09-14

Developing affordable monoclonal antibodies for LMICs through high performance manufacturing processes and LMIC based commercial manufacturing

Abstract: Monoclonal Antibodies (mAbs) are one of the most effective developments in disease prevention and treatment of the last century. Active treatment and passive…

Date: 2026-09-14

Transcriptomics- and machine learning-based identification and mechanistic in vitro validation of a cardiovascular risk gene signature at the CKD–cancer intersection: a multi-omics approach

Abstract: Anticancer treatment-induced cardiovascular toxicity (CTox) represents a critical and emerging challenge in cardio-oncology. Cancer patients with concurrent chronic…

Date: 2026-09-14

Short-term right heart reverse remodeling with vericiguat in HFrEF: reductions in pulmonary arterial pressure and chamber dimensions

Abstract: Heart failure is the end-stage of various cardiovascular diseases. Although a variety of drugs have slowed down the progression of the disease, the prognosis of heart…

Date: 2026-09-14

Leucine, autoimmune diseases, and circulating mediators shape the causal landscape of lymphoid malignancies

Abstract: While genetic abnormalities underlying lymphoid malignancies (LM) are well-characterized, the environmental and metabolic determinants driving LM remain largely…

Date: 2026-09-11

Other primary malignancies are associated with inferior survival in multiple myeloma: a single-center matched retrospective cohort study

Abstract: Other primary malignancies (OPMs) may complicate diagnostic assessment, treatment sequencing, and prognostic evaluation in multiple myeloma (MM). This study…

Date: 2026-09-11

Repurposing a prostate tumor marker: elevated FPSA/TPSA ratio as a novel non-invasive biomarker for declining eGFR in male type 2 diabetes

Abstract: Diabetic kidney disease (DKD) lacks accessible, cost-effective biomarkers for early screening. Given the distinct clearance pathways of free prostate-specific antigen…

Date: 2026-09-11