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From single-cell to spatial transcriptomics: decoding the glioma stem cell niche and its clinical implications

Abstract: Background: Gliomas are aggressive brain tumors associated with a poor prognosis. Cancer stem cells (CSCs) play a significant role in tumor recurrence and resistance to…

Date: 2024-09-17

Secondary traumatic stress and vicarious posttraumatic growth in oncology nurses: the mediating role of empathy

Abstract: Background: The relationship between secondary traumatic stress (STS), empathy, and vicarious post-traumatic growth (VPTG) in oncology nurses is unclear. Understanding…

Date: 2024-09-17

Low brain-derived neurotrophic factor and high vascular cell adhesion molecule-1 levels are associated with chronic kidney disease in patients with type 2 diabetes mellitus

Abstract: Background: Patients with type 2 diabetes mellitus (DM) have a high prevalence of chronic kidney disease (CKD). Energy imbalance and inflammation may be involved in the…

Date: 2024-09-17

Robust and persistent B-cell responses following SARS-CoV-2 vaccine determine protection from SARS-CoV-2 infection

Abstract: Introduction: A clear immune correlate of protection from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has not been defined. We explored…

Date: 2024-09-17

Evaluation of the review models and approval timelines of authorities participating in the East African Medicine Regulatory Harmonisation initiative: alignment and strategies for moving forward

Abstract: Introduction: Medicines regulatory harmonisation has been embraced by many national regulatory authorities (NRAs) to improve public health through faster availability of…

Date: 2024-09-17

Lower extremity muscle activity during reactive balance differs between adults with chronic traumatic brain injury and controls

Abstract: Background: Control of reactive balance is key to achieving safe independent walking and engagement in life activities. After traumatic brain injury (TBI), motor…

Date: 2024-09-17